Results 121 to 130 of about 84,991 (218)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

A case of emphysematous cystitis with significant quantity and atypical gas distribution on CT. [PDF]

Urol Case Rep
Yallapragada S, Gianakopoulos A, Murthy P.   +2 more
europepmc   +1 more source

Robust Spin Splitting and Fermiology in the Layered Altermagnet CoNb4${\rm CoNb}_4$Se8${\rm Se}_8$

Advanced Materials, EarlyView.
The emergence of an altermagnetic phase is demonstrated in the cobalt‐intercalated superconducting 2H‐NbSe2 polymorph. A combined theoretical and experimental approach directly probes the magnetism, the altermagnetic lifting of Kramers degeneracy, and the electronic phase space, establishing CoNb4Se8 as the first g‐wave altermagnetic layered material ...
Alessandro De Vita, Chiara Bigi, Davide Romanin, Matthew D. Watson, Vincent Polewczyk, Marta Zonno, François Bertran, Pietro M. Forcella, My Bang Petersen, Federico Motti, Giovanni Vinai, Manuel Tuniz, Federico Cilento, Mario Cuoco, Brian M. Andersen, Andreas Kreisel, Luciano Jacopo D'Onofrio, Oliver J. Clark, Mark T. Edmonds, Christopher Candelora, Muxian Xu, Siyu Cheng, Alexander LaFleur, Tommaso Antonelli, Giorgio Sangiovanni, Lorenzo Del Re, Ivana Vobornik, Jun Fujii, Fabio Miletto Granozio, Alessia Sambri, Emiliano Di Gennaro, Jeppe B. Jacobsen, Henrik Jacobsen, Iulia Cojocariu, Marcin Szpytma, Andrea Locatelli, Tevfik Mentes, Won Seop Song, Jun Sung Kim, Matthieu Jamet, Jean‐François Jacquot, Pasquale Orgiani, Ralph Ernstorfer, Ilija Zeljkovic, Younghun Hwang, Matteo Calandra, Jill A. Miwa, Federico Mazzola   +47 more
wiley   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Offline Policy Evaluation and Learning with Harm Constraints. [PDF]

Entropy (Basel)
Chaoge J, Yang Q, Li J, Wu P.
europepmc   +1 more source

Dual Single Atoms Boosting Photocatalytic Upcycling of Raw Polyvinylidene Fluoride Plastic

Advanced Materials, EarlyView.
To resolve the catastrophic disaster of plastic contamination, the Cu‐Fe dual‐single‐atom‐loaded In2P3S9 NSs photocatalyst was prepared for direct conversion of raw polyvinylidene fluoride plastic into valuable chemicals. The dual‐single‐atom catalyst exhibits exceptional performance, with a total acetic/formic acid production of ∼1351.8 µmol g−1 ...
Amin Talebian‐Kiakalaieh, Shiying Ren, Wenzhong Ji, Yun Liu, Bingquan Xia, Jingrun Ran, Shi‐Zhang Qiao   +6 more
wiley   +1 more source

Beyond Fat Loss: Addressing the Sarcopenia Challenge of Incretin-Based Therapies. [PDF]

Diabetes Metab J
Kim JY, Kim NH.
europepmc   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Spatiotemporal modeling of GPCR signaling: The role of endosomal dynamics and receptor recycling. [PDF]

PLoS Comput Biol
Weckel C, Gourdon J, Darrigade L, Jugnarain V, Crépieux P, Reiter E, Jean-Alphonse F, Haar S, Yvinec R.   +8 more
europepmc   +1 more source

Kirigami‐Inspired Stretchable Silicon Solar Cell Modules as Portable Power Sources

Advanced Materials, EarlyView.
Kirigami‐inspired structured substrates are designed to craft stretchable silicon solar cell modules, showcasing remarkable stability upon deformation and retaining high output efficiency. This innovative approach holds great promise for the utilization of silicon modules for wearable devices.
Yusheng Zhang, Chenyi Zhang, Pei Wang, Yetai Cheng, Qi Liang, Yonghuan Li, Zhengdong Wei, Huanyu Zhou, Xinyi Kong, Minghua Li, Yifan Wang, Zhishan Bo, Yuqiang Liu, Antonio Facchetti   +13 more
wiley   +1 more source