Results 31 to 40 of about 1,949,204 (276)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Novel reversible data hiding based on difference expansion

open access: yesTongxin xuebao, 2016
A novel reversible data hiding algorithm based on difference expansion called ACD was proposed, which used the so-called adaptive change direction technology. ACD embeds data by expanding the differences of neighboring pixel values.
Jian-gao LUO, Guo-qiang HAN, Yan WO
doaj   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Peningkatan Kualitas Citra Stego pada Adaptive Pixel Block Grouping Reduction Error Expansion dengan Variasi Model Scanning pada Pembentukan Kelompok Piksel

open access: yesJurnal Teknologi Informasi dan Ilmu Komputer, 2018
Kebutuhan komunikasi yang terus bertambah dan ditandai dengan meningkatnya jumlah IP traffic dari 744 EB menjadi 1.164 EB menjadikan keamanan sebagai salah satu kebutuhan utama dalam menjaga kerahasiaan data. Adaptive Pixel Block Grouping Reduction Error
Hendro Eko Prabowo, Tohari Ahmad
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Comparison Of Reversible Image Watermarking Methods Based On Prediction-Errors

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2019
This study compares two reversible imagewatermarking algorithms applied to a digital image. The first algorithm is amethod based on adaptive watermarking of prediction-errors.
Burhan Baraklı, Emre Altınkaya
doaj   +1 more source

High‐quality reversible data hiding scheme using sorting and enhanced pairwise PEE

open access: yesIET Image Processing, 2022
This paper proposes a novel reversible data hiding (RDH) technique using sorting and pairwise prediction error expansion (PEE) to improve embedding capacity (EC) while retaining the quality of cover image.
Gurjinder Kaur   +4 more
doaj   +1 more source

Wafer Level Packaging Technology Applied to Pixel Detectors

open access: yesFrontiers in Physics, 2021
Pixel technology is commonly used in the tracking systems of High Energy Physics detectors with physical areas that have largely increased in the last decades.
Paolo Conci   +9 more
doaj   +1 more source

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