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A naturally occurring NS1 variant with effector domain deletion gains growth advantages in influenza virus infection. [PDF]

open access: yesEmerg Microbes Infect
Tsai RS   +9 more
europepmc   +1 more source

The potential immunological mechanisms of gut microbiota dysbiosis caused by antibiotics exacerbate the lethality of influenza viruses. [PDF]

open access: yesGut Microbes
Zhu J   +13 more
europepmc   +1 more source

Determinant host differences in ZIKV sfRNA accumulation

open access: yes
Ricciardi-Jorge T   +3 more
europepmc   +1 more source
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PKR, apoptosis and cancer

The International Journal of Biochemistry & Cell Biology, 1999
The double-stranded (ds) RNA-regulated serine/threonine protein kinase, PKR, is an interferon-inducible enzyme of widespread occurrence in mammalian cells. PKR is activated by dsRNA via a mechanism involving autophosphorylation. Once activated, the enzyme phosphorylates the alpha-subunit of protein synthesis initiation factor eIF2, thereby inhibiting ...
R, Jagus, B, Joshi, G N, Barber
openaire   +2 more sources

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