Results 121 to 130 of about 211,370 (194)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

PAYMENT FOR WORK AND PROTECTION OF WORKERS, IF PAYMENT NOT RECEIVED: COMPARISON BETWEEN SLOVENIA, AUSTRIA AND SERBIA

open access: yes, 2016
Plača delavca predstavlja, v večini primerov, glavni vir preživetja delavca kot tudi njegove družine. V Sloveniji je velika težava ta, da vedno več delavcev prejema minimalno plačo, ki ne omogoča več preživetja.
Matičič, Natalija
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

The impact of change in the amount of the consumer\u27s minimum creditworthiness

open access: yes
Diplomsko delo obravnava vpliv minimalne plače na kreditno sposobnost potrošnikov in kako so makrobonitetnih omejitve Banke Slovenije vplivale na to sposobnost. Na začetku smo predstavili teorijo kaj je kredit, njegove naloge ter kako ga delimo.
Kotnjek, Domen
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Prispevek k osvetlitvi zaslužkov in cen v srednjeveškem Piranu

open access: yes, 1984
The author deals with three aspects important for life in the medieval Piran: prices (and the living costs connected vvith them), earnings (and possibilities of employment) and the question of »awarding a prize as to one\u27s work«.Članek obravnava tri ...
Mihelič, Darja
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Rural-Focused Nursing Education: A Summative Evaluation of RNs’ Experiences of the Rural Nursing Certificate Program

open access: yesQuality Advancement in Nursing Education, 2015
Martha MacLeod, Jessica Place
doaj   +1 more source

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