Results 61 to 70 of about 212,073 (195)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Future of Sustainable Beef in the United States
AIA Avances en Investigación Agropecuaria, 2014 Cómo se visualiza el futuro de la industria de la carne de bovino en EU y, en tal caso, para toda América del Norte? ¿Será sustentable? ¿Qué se debe entender por una producción de carne de bovino sustentable?
Sara E. Place
doaj
Transcriptome Analysis of Core Dinoflagellates Reveals a Universal Bias towards “GC” Rich Codons
Marine Drugs, 2017 Although dinoflagellates are a potential source of pharmaceuticals and natural products, the mechanisms for regulating and producing these compounds are largely unknown because of extensive post-transcriptional control of gene expression.
Ernest Williams +2 more
doaj +1 more source
Primerjava motivacijskih dejavnikov v dveh lesno predelovalnih podjetjih [PDF]
, 2016 V raziskavi smo analizirali motivacijske in demotivacijske dejavnike med zaposlenimi v dveh lesno predelovalnih podjetjih. Raziskava je potekala v letih 2014 in 2015.
Faletar, Josip +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
HardwareXDescribed here is the construction of a low-cost, standalone underwater camera system designed for recording processes occurring on aquatic substrates. The Submerged Microscope for Observing Substrates (SuMOS) utilizes a Raspberry Pi Zero 2 W paired with
Jens Wira, Allen R. Place
doaj +1 more source
Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes.
PLoS ONE, 2017 Atoh8 is a bHLH transcription factor expressed in pancreas, skeletal muscle, the nervous system, and cardiovascular tissues during embryological development.
Elsie S Place, James C Smith
doaj +1 more source
Success of investment into a detached house in different locations [PDF]
, 2015 The aim of this diploma thesis is to evaluate the market value of a detached house (through the cost method) on different locations in the municipalities of Tržič and Radovljica, as well as determining the success of investment into the real estate in ...
Fajfar, Teja
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source