Results 81 to 90 of about 212,073 (195)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Accelerated evolution at chaperone promoters among Antarctic notothenioid fishes

open access: yesBMC Evolutionary Biology, 2019
Background Antarctic fishes of the Notothenioidei suborder constitutively upregulate multiple inducible chaperones, a highly derived adaptation that preserves proteostasis in extreme cold, and represent a system for studying the evolution of gene ...
Samuel N. Bogan, Sean P. Place
doaj   +1 more source

Lidové písně a tance z Ratíškovic. [PDF]

open access: yes, 2011
Vědecká edice přináší dosud nepublikované lidové písně z obce Ratíškovice a zápisy lidových tanců Milady Bimkové z téže obce.The compiled scientific edition presents the hitherto not published folk songs from the village of Ratíškovice and the folk dance
Bimková Milada   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The impact of determinants of supply and demand on prices in the catering industry [PDF]

open access: yes, 2015
Z metodo glavnih komponent smo ugotovili dve skupni komponenti, s katerima je mogoče pojasniti skupne dejavnike analiziranih spremenljivk, in sicer splošna raven cen in plače v gostinstvu ter uvedba evra, stabilnost cen v evrih in povpraševanje po ...
Bojnec, Štefan, Gričar, Sergej
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Running the Stop Sign: Readthrough of a Premature UAG Termination Signal in the Translation of a Zebrafish (Danio rerio) Taurine Biosynthetic Enzyme

open access: yesMarine Drugs, 2017
The UAG termination codon is generally recognized as the least efficient and least frequently used of the three universal stop codons. This is substantiated by numerous studies in an array of organisms.
Mary E.M. Larkin, Allen R. Place
doaj   +1 more source

Comparison of forest machine cost calculation methods on the case of a cableway [PDF]

open access: yes, 2016
Primerjali smo rezultate kalkulacij neposrednih materialnih stroškov po sedmihuveljavljenih kalkulacijskih metodah za gozdarsko strojno delo. Metode imajo skupno izhodišče pri strukturiranju kalkulacijskih postavk, a se razlikujejo v načinu izračunavanja
Klun, Jaka   +3 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

To be brothers: task and challenge. Variations on the theme of rotherhood in the book of Genesis [PDF]

open access: yes, 2016
Biblijsko razmišljanje na temu bratskih odnosa počinje u Sta- rom zavjetu na pragmatičan način pripoviješću o tragičnom slu- čaju Kajina i Abela (Post 4).
Miljenko Odrljin
core   +1 more source

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