Results 91 to 100 of about 212,073 (195)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Akuzativne dopune zu neprijelazne glagole : što su unutrašnji objekti? [PDF]

open access: yes, 2011
U radu se promatraju akuzativne dopune uz desetak neprijelaznih glagola u hrvatskome jeziku te se razmatra njihova pripadnost kategoriji unutrašnjih objekata.
Birtić, Matea, Matas Ivanković, Ivana
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Sharing, commenting, and reacting to Danish misinformation: A case study of cognitive attraction on Facebook

open access: yesNordicom Review
Social media facilitate a competition for users’ limited attention by bringing various content together, from health advice to entertainment, and from updates from loved ones to misinformation. Especially misinformation has raised societal concern.
Bak Petra de Place, Weed Ethan
doaj   +1 more source

PHILOSOPHICAL AND BIBLICAL ISSUES IN KRANJČEVIĆ’S POETRY th marking the 140 anniversary of Silvije Strahimir Kranjčević’s birthday) [PDF]

open access: yes, 2005
Temu Misaona i biblijska tematika Kranjčevićeva pjesničkog izraza ostvarila sam sa svrhom povezivanja literarnih i teoloških motiva u pjesmama: Mojsije, Zadnji Adam, Golgota, Eli! Eli! Lama sabaktani!? Hristova slika, Angelus, Anđeo bola, Mir vama! Hrist
Vjekoslava Bagarić
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Carbon monoxide exposure in pregnant women in the UK

open access: yesBMC Pregnancy and Childbirth
Background Carbon monoxide (CO) is a colourless, odourless gas that poses a threat to life at concentrations of just a few hundred ppm. The developing foetus is particularly vulnerable to CO exposure, and maternal exposure to much lower levels of the gas
Elsie Place   +2 more
doaj   +1 more source

Rajnski forint – rajniški – u hrvatskom kajkavskom književnom jeziku [PDF]

open access: yes, 2007
U radu se raspravlja o leksikografskom postupku koji se primjenjuje u izradbi Rječnika hrvatskoga kajkavskoga književnog jezika pri uspostavljanju nadnatuknice i kanonskih likova za dvadesetak potvrđenih leksičkih varijanata za ‘rajnski forint’, novčanu ...
Brlobaš, Željka, Vajs, Nada
core   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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