Results 51 to 60 of about 2,514,874 (301)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Solo-Living, Demographic and Family Change: The Need to Know More About Men [PDF]

open access: yes
Solo-living is analytically separate from 'being single' and merits separate study. In most Western countries more men are solo-living than women at ages conventionally associated with co-resident partners and children.
Fran Wasoff   +2 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Are stock exchanges integrated in the world? - A critical Analysis [PDF]

open access: yes
In the recent rapid reforms made the global into a global village in nature and in terms of efficiency, transparency. The information flow in one market may affect the other markets in the world, because of its integration.
Boppana, Nagarjuna, Varadi, Vijay Kumar
core   +1 more source

Hindu-Christian Dialogue: A Review [PDF]

open access: yes, 1988
Hindu-Christian dialogue has had a long and checkered history. Up until the beginning of this century most of the Hindu-Christian interaction took place in India.
Coward, Harold
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Rural Development and the Declining Coherence of Rural Policy: An American and Canadian Perspective [PDF]

open access: yes
Rural development policy in North America has moved from a position of national importance to one of marginality as Canada and the United States grew. While rural policy and agricultural policy are no longer synonymous there is no firm consensus on what ...
Freshwater, David
core   +1 more source

The World of Organic Agriculture - Statistics and Emerging Trends 2004 [PDF]

open access: yes, 2004
In 1999, BioFach/Oekowelt GmbH commissioned Foundation Ecology & Agriculture SOEL to compile statistical data and general information on organic agriculture world-wide. Since then this study has been revised annually, and the newest figures are regularly
Willer, Helga, Yussefi, Minou
core  

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