Results 101 to 110 of about 937,159 (216)

HOLIDAY ATTACHMENT: THE CONSTRUCT AND ITS MEASUREMENT [PDF]

open access: yes
Given that it is not the individual components constituting a holiday in isolation or in simple additive relationship that determines tourists’ sense of satisfaction with that holiday, the absence of an instrument to capture the effect of the holiday ...
Alexandru Nedelea, George P. Babu
core  

Aging on the farm : toward a model of passionate place attachment [PDF]

open access: yes
Title from PDF of title page (University of Missouri--Columbia, viewed on January 26, 2011).Thesis advisor: Ruth Brent Tofle.Vita.Ph. D. University of Missouri--Columbia, 2009.The farm population is aging with 29% of principal farm operators over the age
Ingham, Diana L.
core   +1 more source

Ambivalence in Place Attachment

open access: yesArchitecture and the Built Environment, 2018
This paper focuses on the influence of state-led urban redevelopment on the place attachment of deprived homeowners living in danwei communities that are facing demolition in Shenyang, China. It investigates lived experiences through in-depth interviews with homeowners at the pre-demolition phase.
Xin Li   +2 more
openaire   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

ANTECEDENT AND OUTCOME OF PLACE ATTACHMENT IN HERITAGE SITES [PDF]

open access: yesJournal of Applied Structural Equation Modeling, 2020
Khairunnisak Latiff   +3 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Community Attachment to AlUla Heritage Site and Tourists’ Green Consumption: The Role of Support for Green Tourism Development

open access: yesHeritage
This study explores the interrelationship between community attachment in AlUla Heritage City (located in Saudi Arabia) and tourists’ green consumption practices, testing support for green tourism development as a mediator.
Ibrahim A. Elshaer   +3 more
doaj   +1 more source

A Place Just Right: Effects of Place Attachment on Preference for Restorative Environments [PDF]

open access: yes, 2011
The present study was designed to test whether natural environments are perceived as most restorative by all people regardless of background or whether preference for type of potentially restorative setting varies according to the type of settlement and ...
Mayfield, Mollie
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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