Results 81 to 90 of about 201,612 (307)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Relationship of Place Attachment and Subjective Wellbeing: Heritage City Johor Bahru
International Journal of Built Environment and SustainabilityHeritage cities encompass a wide array of tangible and intangible cultural resources, including historical structures, architectural styles, customs, and cultural environments.
Shahida Nur Nabila Samsur +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Place type or place function: What matters for place attachment?
American Journal of Community Psychology, 2023 AbstractPlace attachment at neighborhood places can facilitate social ties and community belonging, reduce social isolation and improve physical and mental health outcomes. Research highlights the benefits of place attachment at traditional third places such as cafes and parks but is yet to examine place attachment across a broader suite of highly ...
openaire +4 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Place attachment of Ngāi Te Ahi to Hairini Marae
, 2008 Twelve members of Ngāi Te Ahi, a hapū from Tauranga, were interviewed to explore how they talk about their place attachment to Hairini Marae. This was organized around five key dimensions of place attachment taken from the literature—continuity ...
Guerin, Bernard +2 more
core
Linking activity and place attachment dimensions in enhancing the sense of place [PDF]
, 2007 Sense of place definition includes the point where the physical form, activity and meaning are intertwined in the people experience of a place. In urban design and place quality research, much has been discussed on the influence of the physical form ...
Ujang, Norsidah, Dola, Kamariah
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Place attachment among retirees in Greensburg, Kansas
, 2011 On May 4, 2007, an EF-5 tornado passed through Greensburg leveling 95 percent of the town. Because city leaders encouraged everyone to use “green” building techniques as they rebuilt their homes and businesses, not only has the return to normalcy been ...
Smith, Jeffrey S., Cartlidge, Matthew R.
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source