Results 81 to 90 of about 4,146,309 (298)
Place type or place function: What matters for place attachment?
American Journal of Community Psychology, 2023 AbstractPlace attachment at neighborhood places can facilitate social ties and community belonging, reduce social isolation and improve physical and mental health outcomes. Research highlights the benefits of place attachment at traditional third places such as cafes and parks but is yet to examine place attachment across a broader suite of highly ...
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Wait Up!: Attachment and Sovereign Power [PDF]
, 2014 Sociologists and feminist scholars have, over many decades, characterised attachment as a social construction that functions to support political and gender conservatism.
Monica Greco +7 more
core +2 more sources
Public Attachment to Religious Places: A Study of Place Attachment to Mosques in Malaysia
, 2013 {"references": ["Altman, I. and S.M. Low, Place attachment. 1992, New York: Plenum Press.", "Giuliani, M.V. and R. Feldman, Place attachment in a developmental and cultural context. Journal of Environmental Psychology, 1993. 13: p. 267-274.", "Manzo, L.C., Beyond house and haven: Toward a revisioning of emotional relationships with places.
Mina Najafi +1 more
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Place attachment and sustainable behaviour in heritage tourism
, 2018 This paper focuses on the role of place attachment as an important antecedent of sustainable behaviours of visitors in a heritage destination context.
A Marasco, RH Ramkissoon, P Buonincontri
core
Ecology and SocietyGlobally, coastal communities are being shaped by the ongoing movement of people locally, regionally, and internationally. These communities are made up of people with a range of mobility histories, living alongside each other and developing ...
Francois Bousquet +3 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source