Results 101 to 110 of about 4,323,076 (294)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Constructing Geographical Place Attachment in Ritual Tourism of Cities (Yom al-Abbas Ceremony in Zanjan) [PDF]
International Journal of Tourism, Culture and SpiritualityRitual tourism, as a reflection of local identity and culture, plays a significant role in shaping and renewing the tourism experience. This study aims to explain the effect of ritual tourism (with emphasis on the Yom al-Abbas ceremony in Zanjan) on the ...
Alireza Daviran
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
HeritageThis study explores the interrelationship between community attachment in AlUla Heritage City (located in Saudi Arabia) and tourists’ green consumption practices, testing support for green tourism development as a mediator.
Ibrahim A. Elshaer +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Celebrity and film tourist loyalty: Destination image and place attachment as mediators
Journal of Hospitality and Tourism Management, 2023 Bin Zhou +5 more
semanticscholar +1 more source
Place Attachment in Foreign Psychology: Theoretical Approaches and Empirical Research
Современная зарубежная психологияThe article provides an overview of studies of the phenomenon of attachment to place of residence in foreign studies. A comparison of the points of view of foreign researchers on the relationship between the categories “Place Attachment ...
O.R. Tuhina
doaj +1 more source
The Study of the Role of Individual Characteristics on the Users' Devotion to Urban Spaces (The Case Study of KHayyam Avenue of Qazvin City) [PDF]
نشریه جغرافیا و برنامهریزی, 2014 Human and place relationship has different dimensions and place attachment is one the most important emotional dimensions. There are many studies which address to personal characteristics and place features in this relationship.
Maryam Charkhchian
doaj