Results 181 to 190 of about 9,473,872 (308)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Evaluating place cell detection methods in Rats and Humans: Implications for cross-species spatial coding. [PDF]

PLoS Comput Biol
Zhang W, Donoghue T, Qasim SE, Jacobs J.
europepmc   +1 more source

The place-cell representation of volumetric space in rats. [PDF]

Nat Commun, 2020
Grieves RM, Jedidi-Ayoub S, Mishchanchuk K, Liu A, Renaudineau S, Jeffery KJ.   +5 more
europepmc   +1 more source

A Quarter of a Century of Place Cells [PDF]

Neuron, 1996
openaire   +2 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Connecticut Children's Place annual report. 2010.

, 2010
Annual; Began with Feb. 2010.; "Submitted to the State Advisory Council on Children and Families pursuant to Section 17a-32a of the Connecticut General Statutes.
Connecticut Children's Place.
core   +1 more source

Hippocampal Place Cell Sequences Are Impaired in a Rat Model of Fragile X Syndrome. [PDF]

J Neurosci
Donahue MM, Robson E, Colgin LL.
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Mechanisms of experience-dependent place-cell referencing in hippocampal area CA1. [PDF]

Nat Neurosci
Qian FK, Li Y, Magee JC.
europepmc   +1 more source