Results 101 to 110 of about 17,689,950 (324)

Adapting hippocampus multi-scale place field distributions in cluttered environments optimizes spatial navigation and learning

open access: yesFrontiers in Computational Neuroscience, 2022
Extensive studies in rodents show that place cells in the hippocampus have firing patterns that are highly correlated with the animal's location in the environment and are organized in layers of increasing field sizes or scales along its dorsoventral ...
Pablo Scleidorovich   +2 more
doaj   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Do Longer Delays Matter? The Effect of Prolonging Delay in CTL Activation [PDF]

open access: yes, 2010
The activation of a specific immune response takes place in the lymphoid organs such as the spleen. We present here a simplified model of the proliferation of specific immune cells in the form of a single delay equation.
Gallegos, Angela, Radunskaya, Ami
core   +2 more sources

Steps in the neoplastic transformation of hamster embryo cells by polyoma virus [PDF]

open access: yes, 1963
Cultures of hamster embryo cells infected with polyoma virus undergo a characteristic transformation within several weeks after infection. The transformed cultures are constituted by highly atypical cells which have an abnormal morphology, grow rapidly ...
Dulbecco, Renato, Vogt, Marguerite
core   +1 more source

From grid cells to place cells with realistic field sizes

open access: yesPLoS ONE, 2017
While grid cells in the medial entorhinal cortex (MEC) of rodents have multiple, regularly arranged firing fields, place cells in the cornu ammonis (CA) regions of the hippocampus mostly have single spatial firing fields.
Torsten Neher, A. Azizi, Sen Cheng
semanticscholar   +1 more source

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou   +9 more
wiley   +1 more source

Quantitative studies of nucleic acid in the cell by microspectrophotometry III. Nucleic acid contents in the cancer cells [PDF]

open access: yes, 1960
1. The DNA contents in mature lymphocytes of the mouse, rat and man are kept almost constant. 2. The variety in the DNA contents in tumor cells is attributed to the rapid DNA synthesis taking place at the interphase, though the degenerating cells and the
Utsumi, Kozo
core   +1 more source

Spatial Representation of Hippocampal Place Cells in a T-Maze with an Aversive Stimulation

open access: yesFront. Neural Circuits, 2017
The hippocampus contains place cells representing spaces in an environment, and these place cells have been suggested to play a fundamental role in the formation of a cognitive map for spatial processing.
Sakura Okada   +3 more
semanticscholar   +1 more source

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka   +7 more
wiley   +1 more source

Morphogenesis along the animal-vegetal axis: fates of primary quartet micromere daughters in the gastropod Crepidula fornicata. [PDF]

open access: yes, 2017
BackgroundThe Spiralia are a large, morphologically diverse group of protostomes (e.g. molluscs, annelids, nemerteans) that share a homologous mode of early development called spiral cleavage.
Henry, Jonathan Q   +2 more
core   +1 more source

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