Results 111 to 120 of about 16,525,519 (328)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
, 2011 The firing of hippocampal place cells encodes instantaneous location but can also reflect where the animal is heading (prospective firing), or where it has just come from (retrospective firing).
Dudchenko, Paul +11 more
core +1 more source
A boundary vector cell model of place field repetition [PDF]
, 2018 Hippocampal place cells are thought to form the neural substrate of a global cognitive map. However, in multicompartment mazes these cells exhibit locally repeating representations, undermining the global cognitive map view of place cells.
Duvelle, E. +5 more
core +1 more source
Place Cells in Perspective [PDF]
Neuron, 2008 The importance of the hippocampus for learning and memory was first recognized in the late 1950s when William Scoville and Brenda Milner published their account of patient H.M. whose hippocampus was removed during an operation aimed at treating his otherwise intractable epilepsy.
openaire +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Theta-modulated place-by-direction cells in the hippocampal formation in the rat
, 2004 We report the spatial and temporal properties of a class of cells termed theta-modulated place-by-direction (TPD) cells recorded from the presubicular and parasubicular cortices of the rat. The firing characteristics of TPD cells in open-field enclosures
Wills, TJ +4 more
core
Asymmetry of the temporal code for space by hippocampal place cells
Scientific Reports, 2016 Hippocampal place cells convey spatial information through spike frequency (“rate coding”) and spike timing relative to the theta phase (“temporal coding”).
Bryan C. Souza, A. Tort
semanticscholar +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Hippocampal Place Cells Demand Attention [PDF]
Neuron, 2004 Hippocampal representations of the environment are thought to play a fundamental role in the encoding, storage, and retrieval of declarative memory. In this issue of Neuron, Kentros and coworkers show that new hippocampal representations stabilize only when animals are attentive.
openaire +2 more sources
Hippocampal place cells construct reward related sequences through unexplored space
eLife, 2015 Dominant theories of hippocampal function propose that place cell representations are formed during an animal's first encounter with a novel environment and are subsequently replayed during off-line states to support consolidation and future behaviour ...
H. F. Ólafsdóttir +4 more
semanticscholar +1 more source