Results 81 to 90 of about 16,525,519 (328)

ER-Mitochondria Communication in Cells of the Innate Immune System

, 2022
Art. 1088, 21 S.In cells the interorganelle communication comprises vesicular and non-vesicular mechanisms. Non-vesicular material transfer predominantly takes place at regions of close organelle apposition termed membrane contact sites and is ...
Namgaladze, D., Brüne, B., Khodzhaeva, V.   +2 more
core   +1 more source

Firing rate adaptation affords place cell theta sweeps, phase precession, and procession

eLife
Hippocampal place cells in freely moving rodents display both theta phase precession and procession, which is thought to play important roles in cognition, but the neural mechanism for producing theta phase shift remains largely unknown.
Tianhao Chu, Zilong Ji, Junfeng Zuo, Yuanyuan Mi, Wen-hao Zhang, Tiejun Huang, Daniel Bush, Neil Burgess, Si Wu   +8 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Place field repetition and spatial learning in a multicompartment environment [PDF]

, 2016
Recent studies have shown that place cells in the hippocampus possess firing fields that repeat in physically similar, parallel environments. These results imply that it should be difficult for animals to distinguish parallel environments at a behavioral
Grieves, Roddy M., Dudchenko, Paul, Dudchenko, Paul A, Wood, Emma R, Grieves, Roderick, Harland, Bruce, Jenkins, Bryan W   +6 more
core   +1 more source

Synchronous ensembles of hippocampal CA1 pyramidal neurons during novel exploration

eLife
Synchronous neuronal ensembles play a pivotal role in the consolidation of long-term memory in the hippocampus. However, their organization during the acquisition of spatial memory remains less clear.
En-Li Chen, Tsai-Wen Chen, Eric R Schreiter, Bei-Jung Lin   +3 more
doaj   +1 more source

In vivo Calcium Imaging Reveals That Cortisol Treatment Reduces the Number of Place Cells in Thy1-GCaMP6f Transgenic Mice

Frontiers in Neuroscience, 2019
The hippocampus, a structure essential for spatial navigation and memory undergoes anatomical and functional changes during chronic stress. Here, we investigate the effects of chronic stress on the ability of place cells to encode the neural ...
Tim Indersmitten, Michael J. Schachter, Stephanie Young, Natalie Welty, Stephani Otte, Jonathan J. Nassi, Timothy Lovenberg, Pascal Bonaventure, Ryan M. Wyatt   +8 more
doaj   +1 more source

Linear Self-Motion Cues Support the Spatial Distribution and Stability of Hippocampal Place Cells

Current Biology, 2018
In Brief Harvey et al. describe how place cells from otoconia-deficit mice become unstable over sessions and show a tendency to form place fields along environmental boundaries.
Ryan E. Harvey, Stephanie A. Rutan, Gabrielle R. Willey, J. J. Siegel, B. J. Clark, Ryan M. Yoder   +5 more
semanticscholar   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Heterogeneous modulation of place cell firing by changes in context

, 2003
Hippocampal place cells show spatially localized activity that can be modulated by both geometric information ( e. g., the distances and directions of features in the environment) and nongeometric information (e.g., colors, odors, and possibly behaviors).
Anderson, MI, Michael I. Anderson, Anderson, Michael I., Jeffery, KJ, Kathryn J. Jeffery, Jeffery, Kathryn J.   +5 more
core   +1 more source

Characterization of lymph node stromal cells during Treg-mediated tolerance [PDF]

, 2013
Solid organs transplantation is therapy of choice for several human diseases. The success of this treatment is determined by the recipientÕs ability to prevent rejection.
Broggi, Maria Anna Sofia
core   +1 more source