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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
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Place Cell’s Computational Model
2022Hippocampal Place Cells play a pivotal role in spatial navigation. These cells have the particular characteristic of firing at a low rate during navigation throughout most of the environment, except when the animal is within a restricted spatial region called place field.
Camille Mazzara +2 more
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Nature Biotechnology, 2015
A combination of single-cell transcriptomics with in situ hybridization information enables single cells to be positioned within their tissue.
Omid R Faridani, Rickard Sandberg
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A combination of single-cell transcriptomics with in situ hybridization information enables single cells to be positioned within their tissue.
Omid R Faridani, Rickard Sandberg
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The overdispersion in activity of place cells
Neurocomputing, 2001Abstract The spontaneous discharge of place cells reflects the position of an animal in its environment. The firing rate is high inside a part of it, called the firing field, and low outside. It has been found experimentally that while the activity of place cells is highly reliable in position, it does not retain the same reliability in time.
Petr Lánský +2 more
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Neuron, 2021
Hippocampal place cells are known to process path integration signals and sensory information about landmarks. In this issue of Neuron, Fischler-Ruiz et al., 2021 show how localized olfactory cues interact with path integration to drive place cells, turning the cues into landmarks.
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Hippocampal place cells are known to process path integration signals and sensory information about landmarks. In this issue of Neuron, Fischler-Ruiz et al., 2021 show how localized olfactory cues interact with path integration to drive place cells, turning the cues into landmarks.
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Making the case for place cells
Nature Reviews Neuroscience, 2020Optogenetic stimulation of place cells alters memory-guided spatial navigation in mice, providing evidence for a causal role for these cells in spatial cognition.
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Place cells in the ventral hippocampus of rats
NeuroReport, 1994Many cells recorded from the dorsal hippocampus of freely moving rats are intensely active only when the rat's head is in a particular part of its environment. For this reason, such units are called 'place cells'. We have investigated whether place cells are also found in the ventral hippocampus.
Poucet, Bruno +2 more
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Science, 2021
Imaging Despite considerable progress in recent years, pathological analysis of tissues and organs often still relies on old-fashioned microscopic techniques. Similarly, genomic and transcriptomic analysis is commonly applied to bulk tissue samples. To address the limitations of these approaches, Zhao et al. and van Ineveld et al.
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Imaging Despite considerable progress in recent years, pathological analysis of tissues and organs often still relies on old-fashioned microscopic techniques. Similarly, genomic and transcriptomic analysis is commonly applied to bulk tissue samples. To address the limitations of these approaches, Zhao et al. and van Ineveld et al.
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Is the place cell a “supple” engram?
Hippocampus, 2015ABSTRACTThis short note, which honors Nobelists O'Keefe and the Mosers, asks how the patterning of inputs to a single place cell regulates its firing. Because the combination of inputs to a single CA1 place cell is very large, the generally accepted view is rejected that inputs to a place cell are relatively restricted, near identical repetition upon ...
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Challenges for Place and Grid Cell Models
2021This chapter gives a short overview of computational models dealing with two fundamental building blocks in spatial cognition: grid and place cells, and of the open issues such models may help address.
Soldatkina, Oleksandra +2 more
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