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Impaired spatial memory codes in a mouse model of Rett syndrome
The Mecp2+/- mouse model recapitulates many phenotypes of patients with Rett syndrome (RTT), including learning and memory deficits. It is unknown, however, how the disease state alters memory circuit functions in vivo in RTT mice.
Sara E Kee +3 more
doaj +1 more source
Spatial navigation and multiscale representation by hippocampal place cells [PDF]
Hippocampal lesions are known to impair success in navigation tasks. While such tasks could be solved by memorizing complete paths from a starting location to the goal, animals still perform successfully when placed in a novel starting position.
Jason S. Prentice +2 more
core +2 more sources
Place, space and memory cells [PDF]
SummarySelf-localization and navigation are critical functions for the survival of mobile animals. By processing sensory information such as landmarks and environmental features, as well as keeping track of the path they have taken, animals are able to remain oriented as they explore the world, learning what resources are where and planning how to ...
Marozzi, Elizabeth, Jeffery, Kathryn J.
openaire +2 more sources
The Growing Evidence for the Importance of the Otoliths in Spatial Memory
Many studies have demonstrated that vestibular sensory input is important for spatial learning and memory. However, it has been unclear what contributions the different parts of the vestibular system – the semi-circular canals and otoliths – make to ...
Paul F. Smith +2 more
doaj +1 more source
Linear Self-Motion Cues Support the Spatial Distribution and Stability of Hippocampal Place Cells [PDF]
The vestibular system provides a crucial component of place-cell and head-direction cell activity [1-7]. Otolith signals are necessary for head-direction signal stability and associated behavior [8, 9], and the head-direction signal's contribution to ...
Clark, Benjamin J. +5 more
core +1 more source
Most vertebrates use active sensing strategies for perception, cognition and control of motor activity. These strategies include directed body/sensor movements or increases in discrete sensory sampling events. The weakly electric fish, Gymnotus sp., uses
Haleh Fotowat +3 more
doaj +1 more source
Biomimetic SLAM Algorithm Based on Growing Self-Organizing Map
A Biomimetic SLAM Algorithm Based on Growing Self-Organizing Map (GSOM-BSLAM), inspired by spatial cognitive mechanism of mammalian hippocampus, is proposed to resolve uncertainty problems in location identification and lack of real-time performance in ...
Yukun Zhang +3 more
doaj +1 more source
Parallel and convergent processing in grid cell, head-direction cell, boundary cell, and place cell networks. [PDF]
The brain is able to construct internal representations that correspond to external spatial coordinates. Such brain maps of the external spatial topography may support a number of cognitive functions, including navigation and memory.
Brandon, Mark P +2 more
core +2 more sources
Intracellular Dynamics of Virtual Place Cells [PDF]
The pattern of spikes recorded from place cells in the rodent hippocampus is strongly modulated by both the spatial location in the environment and the theta rhythm. The phases of the spikes in the theta cycle advance during movement through the place field.
Romani, Sandro +2 more
openaire +2 more sources
Differential Impact of Acute and Chronic Stress on CA1 Spatial Coding and Gamma Oscillations
Chronic and acute stress differentially affect behavior as well as the structural integrity of the hippocampus, a key brain region involved in cognition and memory.
Anupratap Tomar +2 more
doaj +1 more source

