Results 21 to 30 of about 17,689,950 (324)
Methodological Caveats in the Detection of Coordinated Replay between Place Cells and Grid Cells
At rest, hippocampal “place cells,” neurons with receptive fields corresponding to specific spatial locations, reactivate in a manner that reflects recently traveled trajectories.
John B. Trimper +10 more
doaj +2 more sources
Simultaneous monitoring of animal behavior and neuronal activity in the brain enables us to examine the neural underpinnings of behaviors. Conventionally, the neural activity data are buffered, amplified, multiplexed, and then converted from analog to ...
Kaoru Ide, Susumu Takahashi
doaj +1 more source
Dorsal CA1 Hippocampal Place Cells Form a Multi-Scale Representation of Megaspace
Spatially firing “place cells” within the hippocampal CA1 region form internal maps of the environment necessary for navigation and memory. In rodents, these neurons have been almost exclusively studied in small environments (
B. Harland +3 more
semanticscholar +1 more source
Macrophage morphological plasticity and migration is Rac signalling and MMP9 dependant
In vitro, depending on extracellular matrix (ECM) architecture, macrophages migrate either in amoeboid or mesenchymal mode; while the first is a general trait of leukocytes, the latter is associated with tissue remodelling via Matrix Metalloproteinases ...
Jana Travnickova +6 more
doaj +1 more source
Spatial cognition and the avian hippocampus: Research in domestic chicks
In this review, we discuss the functional equivalence of the avian and mammalian hippocampus, based mostly on our own research in domestic chicks, which provide an important developmental model (most research on spatial cognition in other birds relies on
Anastasia Morandi-Raikova, Uwe Mayer
doaj +1 more source
Place cells and place navigation [PDF]
The assumption that hippocampal place cells (PCs) form the neural substrate of cognitive maps can be experimentally tested by comparing the effect of experimental interventions on PC activity and place navigation. Conditions that interfere with place navigation (darkness, cholinergic blockade) but leave PC activity unaffected obviously ...
J, Bures +3 more
openaire +2 more sources
Hippocampus Maintains a Coherent Map Under Reward Feature–Landmark Cue Conflict
Animals predominantly use salient visual cues (landmarks) for efficient navigation. When the relative position of the visual cues is altered, the hippocampal population exhibits heterogeneous responses and constructs context-specific spatial maps ...
Indrajith R. Nair +2 more
doaj +1 more source
‘Fearful-place’ coding in the amygdala-hippocampal network
Animals seeking survival needs must be able to assess different locations of threats in their habitat. However, the neural integration of spatial and risk information essential for guiding goal-directed behavior remains poorly understood.
Mi-Seon Kong +6 more
doaj +1 more source
Rapid learning of predictive maps with STDP and theta phase precession
The predictive map hypothesis is a promising candidate principle for hippocampal function. A favoured formalisation of this hypothesis, called the successor representation, proposes that each place cell encodes the expected state occupancy of its target ...
Tom M George +3 more
doaj +1 more source
Mechanisms for Cognitive Impairment in Epilepsy: Moving Beyond Seizures
There has been a major emphasis on defining the role of seizures in the causation of cognitive impairments like memory deficits in epilepsy. Here we focus on an alternative hypothesis behind these deficits, emphasizing the mechanisms of information ...
Mohamed R. Khalife +6 more
doaj +1 more source

