Results 51 to 60 of about 2,280,368 (270)

Goal-Related Activity in Hippocampal Place Cells [PDF]

The Journal of Neuroscience, 2007
Place cells are hippocampal neurons whose discharge is strongly related to a rat's location in its environment. The existence of place cells has led to the proposal that they are part of an integrated neural system dedicated to spatial navigation, an idea supported by the discovery of strong relationships between place cell activity and spatial problem
Hok, Vincent, Lenck-Santini, Pierre-Pascal, Roux, Sébastien, Save, Etienne, Muller, Robert U., Poucet, Bruno   +5 more
openaire   +3 more sources

Grid Cell Hexagonal Patterns Formed by Fast Self-Organized Learning within Entorhinal Cortex [PDF]

, 2009
Grid cells in the dorsal segment of the medial entorhinal cortex (dMEC) show remarkable hexagonal activity patterns, at multiple spatial scales, during spatial navigation. How these hexagonal patterns arise has excited intense interest. It has previously
Alonso, Berke, Blair, Boucheny, Burak, Burgess, Burgess, Carpenter, Carpenter, Carpenter, Carpenter, Carpenter, Egorov, Frank, Fuhs, Giocomo, Gorchetchnikov, Grossberg, Grossberg, Grossberg, Grossberg, Grossberg, Grossberg, Hafting, Hafting, Hasselmo, Hasselmo, Hasselmo, Klink, Klink, McNaughton, Mhatre, Mhatre, Muller, O'Keefe, Olson, Redish, Rolls, Sargolini, Sharp, Skaggs, Solstad, Song, Taube, Thompson, Wilson   +45 more
core   +2 more sources

Transcriptional repressor ZEB2 promotes terminal differentiation of CD8⁺ effector and memory T cell populations during infection [PDF]

, 2015
ZEB2 is a multi-zinc-finger transcription factor known to play a significant role in early neurogenesis and in epithelial-mesenchymal transition-dependent tumor metastasis.
Agata Stryjewska, Alexander Weidemann, Ananda W. Goldrath, Best, Bingfei Yu, Brabletz, Cannarile, Christiane Zweier, Conidi, Danny Huylebroeck, Engel, Eve Seuntjens, Garavelli, Gattinoni, Goldrath, Goossens, Goossens, Grégoire, Gründemann, Hand, Haring, Harney, Harney, Harty, Higashi, Higashi, Hikono, Hikono, Hisato Kondoh, J. Adam Best, Jessica V. Nguyen, Jody Haigh, Joshi, Kaech, Kaech, Kaech, Kaech, Kallies, Knell, Kyla D. Omilusik, Larabee, Lin, Luca Gattinoni, Lynne M. Bird, Massari, Masson, Mowat, Murre, Olson, Postigo, Postigo, Rahul Roychoudhuri, Remacle, Rice, Rubinstein, Sarkar, Sawada, Sekido, Seuntjens, Steven Goossens, Takemoto, Van de Putte, van den Berghe, van Grunsven, Verschueren, Verstappen, Voehringer, Williams, Wirth, Yang, Yasui, Yujiro Higashi, Zweier   +72 more
core   +3 more sources

Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]

, 2012
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Aisenbrey, Alcazar, Alge, Bhutto, Bodaghi, Burke, Campochiaro, Christoph Szober, Chu, Claudia Alge-Priglinger, Clegg, Cornelia Deeg, Deeg, Deeg, Deeg, Deeg, Deeg, Degroote, Doherty, Dunn, Eberhardt, Ehrenhofer, Greer, Gullapalli, Gundersen, Ham, Hamel, Hauck, Hauck, Hauck, Hauck, Ho, Huang, Karl, Kerstin Euler, Kristina Fröhlich, Li, Limb, Machemer, Marius Ueffing, McBee, Milyushina, Mochizuki, Muramatsu, Nagai, Parker, Philp, Rizzolo, Rotilio, Singer, Stefanie Hauck, Strauss, Vacanti, Wolf, Wu   +54 more
core   +3 more sources

From grid cells and visual place cells to multimodal place cell: a new robotic architecture

Frontiers in Neurorobotics, 2015
In the present study, a new architecture for the generation of grid cells (GC) was implemented on a real robot. In order to test this model a simple place cell (PC) model merging visual PC activity and GC was developed. GC were first built from a simple "several to one" projection (similar to a modulo operation) performed on a neural field coding for ...
Jauffret, Adrien, Cuperlier, Nicolas, Gaussier, Philippe   +2 more
openaire   +3 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Unsupervised Detection of Cell-Assembly Sequences by Similarity-Based Clustering

Frontiers in Neuroinformatics, 2019
Neurons which fire in a fixed temporal pattern (i.e., “cell assemblies”) are hypothesized to be a fundamental unit of neural information processing. Several methods are available for the detection of cell assemblies without a time structure. However, the
Keita Watanabe, Keita Watanabe, Tatsuya Haga, Masami Tatsuno, David R. Euston, Tomoki Fukai, Tomoki Fukai, Tomoki Fukai   +7 more
doaj   +1 more source

Columbanus, charisma and the revolt of the monks of Bobbio [PDF]

, 2008
The account of the revolt of the monks of Bobbio against Columbanus’ successor Attala by Jonas of Bobbio gives only some clues as to why it took place, but suggests that Attala was lacking charisma.
Dunn, M.
core   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Acute silencing of hippocampal CA3 reveals a dominant role in place field responses. [PDF]

, 2019
Neurons in hippocampal output area CA1 are thought to exhibit redundancy across cortical and hippocampal inputs. Here we show instead that acute silencing of CA3 terminals drastically reduces place field responses for many CA1 neurons, while a smaller ...
Davoudi, Heydar, Foster, David J
core