Results 71 to 80 of about 2,280,368 (270)

Synchronous ensembles of hippocampal CA1 pyramidal neurons during novel exploration

eLife
Synchronous neuronal ensembles play a pivotal role in the consolidation of long-term memory in the hippocampus. However, their organization during the acquisition of spatial memory remains less clear.
En-Li Chen, Tsai-Wen Chen, Eric R Schreiter, Bei-Jung Lin   +3 more
doaj   +1 more source

In vivo Calcium Imaging Reveals That Cortisol Treatment Reduces the Number of Place Cells in Thy1-GCaMP6f Transgenic Mice

Frontiers in Neuroscience, 2019
The hippocampus, a structure essential for spatial navigation and memory undergoes anatomical and functional changes during chronic stress. Here, we investigate the effects of chronic stress on the ability of place cells to encode the neural ...
Tim Indersmitten, Michael J. Schachter, Stephanie Young, Natalie Welty, Stephani Otte, Jonathan J. Nassi, Timothy Lovenberg, Pascal Bonaventure, Ryan M. Wyatt   +8 more
doaj   +1 more source

In vivo characterization of hippocampal electrophysiological processes in the heterozygous Pten knockout model of autism [PDF]

, 2018
While cognitive deficits have been described in the heterozygous Pten (+/-) KO mouse model of autism, little work has been done to demonstrate how corresponding in vitro physiological alterations in this model may underpin these cognitive deficits in ...
Barry, Jeremy, Spinella, Anthony J, Weston, Matthew   +2 more
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Differences in firing patterns along the dorsal-intermediate hippocampal axis in a fixed route during a change in emotional context

Frontiers in Systems Neuroscience
The hippocampus plays a prominent role in spatial navigation and memory. However, differences exist along the hippocampus longitudinal axis in function and connectivity.
Ryan Troha, Shang Lin (Tommy) Lee, Maya Anam, Sheela Tavakoli, Bailey Morte, Ian H. Stevenson, Etan J. Markus   +6 more
doaj   +1 more source

Neural Dynamics Indicate Parallel Integration of Environmental and Self-Motion Information by Place and Grid Cells

Frontiers in Neural Circuits, 2019
Place cells and grid cells in the hippocampal formation are thought to integrate sensory and self-motion information into a representation of estimated spatial location, but the precise mechanism is unknown.
Dmitri Laptev, Dmitri Laptev, Neil Burgess   +2 more
doaj   +1 more source

The little brain and the seahorse: Cerebellar-hippocampal interactions

Frontiers in Systems Neuroscience, 2023
There is a growing appreciation for the cerebellum beyond its role in motor function and accumulating evidence that the cerebellum and hippocampus interact across a range of brain states and behaviors.
Jessica M. Froula, Shayne D. Hastings, Esther Krook-Magnuson   +2 more
doaj   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Temporal context and latent state inference in the hippocampal splitter signal

eLife, 2023
The hippocampus is thought to enable the encoding and retrieval of ongoing experience, the organization of that experience into structured representations like contexts, maps, and schemas, and the use of these structures to plan for the future. A central
Éléonore Duvelle, Roddy M Grieves, Matthijs AA van der Meer   +2 more
doaj   +1 more source

Half-Sandwich Ir(III) and Os(II) Complexes of Pyridyl-Mesoionic Carbenes as Potential Anticancer Agents [PDF]

, 2019
A series of cationic chlorido arene-iridium(III) and arene-osmium(II) complexes with bidentate pyridyl functionalized mesoionic carbenes (MIC) of the 1,2,3-triazol-5-ylidene type have been prepared.
Bolje, Aljoša, Brozović, Anamaria, Gržan, Tena, Hohloch, Stephan, Košmrlj, Janez, Kralj, Juran, Osmak, Maja, Sarkar, Biprajit, Steiner, Ivana, Stojanović, Nikolina, Stupin Polančec, Darija, Tupek, Ana, Urankar, Damijana   +12 more
core   +1 more source