Results 181 to 190 of about 5,637,228 (331)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Iterated function systems with continuous place dependent probabilities.

open access: yes, 2002
Summary: We study the asymptotic behaviour of iterated function systems built of a finite number of contractions and positive, continuous, place dependent probabilities. We prove that these systems have some special property which is called quasistability. We also establish the existence of an invariant distribution for such systems.
openaire   +2 more sources

Impact of Gating Characteristics On Place Dependence In FESTAC Housing Estate, Nigeria

open access: yes
The evolutions of urban spaces has brought about diverse residential typologies which often end up as gated. This has implications for behavioural outcomes. The study examines the impact of gating characteristics on placed dependence in urban residential
Solaja, Ayoola   +3 more
core  

Studies of the electrical properties and electroforming of thin insulating films

open access: yes, 1973
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Evaporated thin film sandwich structures of Au-SiOX-Au have been studied.
Gould, Robert David
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Adolescent Exposure to Nicotine and Ethanol Attenuates Adult Nicotine Reward Sensitivity in Rats. [PDF]

open access: yesNeuropsychopharmacol Rep
Toyoshima M   +5 more
europepmc   +1 more source

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