Results 91 to 100 of about 554,526 (268)

Supportive interpersonal communication as an antecedent for effective management

open access: yes, 2009
The effects of positive relationships are much stronger and more long-lasting than just making people happy or uplifted. When individuals are able to build relationships that are positive and that create energy, important physiological, emotional ...
Khan, Ashik Imran   +1 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Lumen-apposing covered self-expanding metal stent for management of benign gastrointestinal strictures

open access: yesEndoscopy International Open, 2016
Background and aims: Self-expanding metal stents (SEMS) are safe and effective for endoscopic management of malignant gastrointestinal strictures, but there is limited experience with their use in refractory benign strictures.
Shounak Majumder   +8 more
doaj   +1 more source

Sport management students in ‘the hot seat’ : a preliminary analysis of the opportunities and challenges associated with using virtual learning and teaching environments

open access: yes, 2013
The emergence and spread of technology, including the internet, continued and rapid development of mobile phone technology and social media platforms are fundamentally altering the way contemporary sport and other service and entertainment orientated ...
O'Shea, Michelle (R12365)
core  

Measuring place branding strategy implementation [Elektronisk resurs]

open access: yes, 2023
Place branding caught significant attention both among researchers and practitioners in the last decades, moving from corporate branding and marketing concept to a more multidisciplinary approach. Being an influential part of new public management, urban
Rauhut Kompaniets, Olga,   +1 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The emerging role of corporate information systems: An example from the area of business process-oriented learning [PDF]

open access: yesInternational Journal of Business Science and Applied Management, 2008
Emerging business requirements, stemming from a holistic view over an organisation’s activities, place additional pressure on technical infrastructures and call for operational agility and a better alignment between business and technology.
Stergioulas, L.K., Pappa, D.
doaj  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Value chain management : a model for co-operation or a conflict?

open access: yes, 2005
Industry-level value chain analysis is an effective way to identify the interplay between different players in any specific industry. It helps identify the resources required successfully to compete in an industry and where individual organisations ...
Hyland, Paul W.   +3 more
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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