Results 71 to 80 of about 554,526 (268)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Regional Governance bei Gemeinschaftsgütern des Ressourcenschutzes: das Beispiel Biosphärenreservate
Raumforschung und Raumordnung, 2005 The article discusses the potentials of using patterns of regional governance for natural resource management (e.g. water, nature protection, landscape formation). The empirical basis refers to biosphere reserves.
Dietrich Fürst +2 more
doaj +1 more source
Framework for effective public digital records management in Uganda
, 2010 This thesis examines the framework for effective management of digital records in Uganda, which was undertaken by a detailed study of the 23 ministries, which form the Uganda Public Service (UPS).
Luyombya, D.
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The practice of risk management by cost consultants in Northern Ireland
, 2010 This research endeavoured to explore the practice of risk management by cost consultants in Northern Ireland. It attempted to subjectively investigate the cost consultant’s appreciation of risk management practices and then further appraise the cost ...
Mc Namee, Maria +3 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Il Capitale Culturale: Studies on the Value of Cultural Heritage, 2016 L’obiettivo della ricerca è proporre una possibile strategia di sviluppo economico sostenibile del comune di Fiordimonte (MC), incardinata sulla valorizzazione a fini turistici delle risorse place e time specific, nell’ottica della resource-based theory.
Elisabetta Maroni
doaj +1 more source
Appreciative inquiry : how does it support management development?
, 2006 This paper outlines the potential of Appreciative Inquiry (AI) in developing new understandings via Management Development initiatives; it is based upon semi-structured interviews with a management development consultant who has used AI for development ...
Blackman, Deborah A. +2 more
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Place of effective management - who calls the shots? [PDF]
, 2016 A research report submitted to the faculty of Commerce, Law and Management, University of the Witwatersrand, Johannesburg in fulfilment of the requirements for the degree of Master of Commerce (specialising in Taxation).
Du Toit, Jaco M
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source