Results 61 to 70 of about 554,526 (268)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Dynamic simulation for effective workforce management in new product development [PDF]
Management Science Letters, 2012 Effective planning and management of workforce for new product development (NPD) projects is a great challenge to many organisations, especially in the presence of engineering changes during the product development process.
M. Mutingi
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Effective social support resources in self- management of diabetic patients in Bushehr (2011-12)
Iranian South Medical Journal, 2013 Background: Diabetes is a serious problem and self- management is effective factor for diabetes control. Social support is one of the important factors in diabetes self-management.
Azita Noroozi +2 more
doaj
The evolutionary ‘waves’ of place-shaping: pre, during and post recession
, 2011 This paper is concerned with the evolution of place-shaping over the past decade or so and its potential future direction, specifically relating to a UK context but with varying aspects of resonance internationally.
Pugalis, L, Pugalis, Lee
core
Complaint Mechanisms in Border Management and Expulsion Operations in Europe: Effective remedies for victims of human rights violations? CEPS Paperback, 26 March 2018 [PDF]
, 2018 Border control, surveillance operations and expulsion of irregular immigrants – particularly through return flights – can pose serious challenges to human rights.
Stefan, Marco, Carrera, Sergio
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2015 The purpose of this study is to investigate the impacts of green supply chain management (GSCM) practices on triple bottom line (TBL) measures. Fuzzy AHP is employed to reveal a relative weight of importance of each GSCM practice on TBL measures, based ...
P. Thamsatitdej +7 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Place-based drivers and effective management of population growth and change in regional Australia [PDF]
AHURI is a national independent research network with an expert not-for-profit research management company, AHURI Limited, at its centre. AHURI’s mission is to deliver high quality research that influences policy development and practice change to ...
Marshall, Nancy +16 more
core +1 more source