Results 141 to 150 of about 1,543,966 (410)

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Effect of Remifentanil on Intra-Ocular Pressure in Cataract Surgery under General Anesthesia with Isoflurane

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2009
BACKGROUND AND OBJECTIVE: One of the important aims in anesthetic management during ocular surgery is to provide adequate control of intraocular pressure (IOP) and increasing of this pressure would cause some dramatic complications even though visual ...
MR Ghodrati,, A Shakeri, N Farnoush, A Shakeri,   +3 more
doaj  

Placebo Effect in the Treatment of Depression and Anxiety

Frontiers in Psychiatry, 2019
The aim of this review is to evaluate the placebo effect in the treatment of anxiety and depression. Antidepressants are supposed to work by fixing a chemical imbalance, specifically, a lack of serotonin or norepinephrine in the brain.
Irving Kirsch
doaj   +1 more source

Rolofylline, an adenosine A1−receptor antagonist, in acute heart failure [PDF]

, 2010
Background: Worsening renal function, which is associated with adverse outcomes, often develops in patients with acute heart failure. Experimental and clinical studies suggest that counterregulatory responses mediated by adenosine may be involved. We
Bloomfield, Daniel M, Cleland, John G F, Cotter, Gad, DeLucca, Paul, Dittrich, Howard C, Fu, Michael,, Givertz, Michael M, Mansoor, George A, Massie, Barry M, Metra, Marco, O'Connor, Christopher M, Ponikowski, Piotr, Salerno, Christina M, Teerlink, John R, Voors, Adriaan, Weatherley, Beth Davison   +15 more
core   +1 more source

A Placebo Controlled Crossover Trial of Liquid Fluoxetine on Repetitive Behaviors in Childhood and Adolescent Autism [PDF]

, 2004
Eric Hollander, Ann Phillips, William F. Chaplin, Karen Zagursky, Sherie Novotny, Stacey Wasserman, Rupa Iyengar   +6 more
openalex   +1 more source

Vitamin D3 and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial): study protocol for a randomised placebo-controlled trial [PDF]

, 2022
Nyasha Dzavakwa, Molly Chisenga, Grace McHugh, Suzanne Filteau, Celia L. Gregson, Lackson Kasonka, Katharina Kranzer, Hildah Banda Mabuda, Hilda Mujuru, Nicol Redzo, Sarah Rowland‐Jones, Ulrich E. Schaible, Victoria Simms, Rashida A. Ferrand   +13 more
openalex   +1 more source

Probiotic‐Based Materials as Living Therapeutics

Advanced Materials, EarlyView.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio, Graham J. Day, Manuel Salmeron‐Sanchez   +2 more
wiley   +1 more source

El efecto placebo y el dolor

Revista Argentina de Reumatología, 2014
Al administrar un medicamento se generan una serie de efectos independientes de la acción farmacológica del principio activo. Estos efectos suelen ser de naturaleza biológica mecanismo de acción de la droga) o psicológica.
Dario Scublinsky
doaj   +1 more source

Golimumab, a human anti–tumor necrosis factor α monoclonal antibody, injected subcutaneously every four weeks in methotrexate‐naive patients with active rheumatoid arthritis: Twenty‐four–week results of a phase III, multicenter, randomized, double‐blind, placebo‐controlled study of golimumab before methotrexate as first‐line therapy for early‐onset rheumatoid arthritis [PDF]

, 2009
Paul Emery, Roy Fleischmann, Larry W. Moreland, Elizabeth C. Hsia, Ingrid Strusberg, Patrick Durez, Peter Nash, Eric Amante, Melvin Churchill, Won Park, Bernardo A. Pons‐Estel, Mittie K. Doyle, Sudha Visvanathan, Weichun Xu, Mahboob U. Rahman   +14 more
openalex   +1 more source

Are there placebo or nocebo effects in balancing performance? [PDF]

, 2023
Áron Horváth, Attila Szabó, Vera Gál, Csilla Suhaj, Blanka Aranyosy, Ferenc Köteles   +5 more
openalex   +1 more source