Results 11 to 20 of about 1,192,795 (361)
Fremanezumab for the Preventive Treatment of Chronic Migraine. [PDF]
BACKGROUND: Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP), is being investigated as a preventive treatment for migraine.
Aycardi, Ernesto +9 more
core +2 more sources
A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]
Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George +15 more
core +2 more sources
An Evolutionary Perspective on Pain Communication
Pain serves as a signal to elicit care from others. In turn, displaying pain might be attractive because of the benefits it might bring. Additionally, displaying pain is easy, because helpers distinguish poorly between genuine pain and faked pain. Hence,
Leander Steinkopf
doaj +1 more source
Topical Tocopherol for treatment of reticular oral lichen planus: randomized, double-blind, crossover study [PDF]
This randomized, double-blind, placebo-controlled crossover study assessed the efficacy of topical tocopherol acetate compared with placebo in easing oral discomfort in patients with reticular oral lichen planus (ROLP)
Bacci, Christian +5 more
core +1 more source
Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S. +8 more
core +2 more sources
Introducción: El bloqueo del nervio peri prostático con lidocaína, proporciona un buen alivio del dolor en la realización de la biopsia prostática guiada por ultrasonido, pero el dolor post-procedimiento, puede llegar a ser significativo, la adición del ...
Jasson Lavi +5 more
doaj +1 more source
Music interventions accommodate the profound need for non-pharmacological pain treatment. The analgesic effect of listening to music has been widely demonstrated across studies. Yet, the specific mechanisms of action have still to be elucidated. Although
Sigrid Juhl Lunde +8 more
doaj +1 more source
The effect of carbohydrate ingestion on the Interleukin-6 response to a 90-minute run time trial [PDF]
Fatigue is a predictable outcome of prolonged physical activity; yet its biological cause remains uncertain. During exercise, a polypeptide messenger molecule interleukin- 6 (IL-6) is actively produced.
Ansley, Les +3 more
core +1 more source
NEW POSSIBILITIES FOR LOCAL THERAPY OF BACK PAIN SYNDROME
Purpose of study – to examine effectiveness and tolerability of therapy рatch NANOPLAST forte in comparison with “placebo” patch in patients with back pain syndrome in conditions of prospective comparative randomized study, approved by the local ethics ...
N. A. Shostak +2 more
doaj +1 more source
Mixed Spices at Culinary Doses Have Prebiotic Effects in Healthy Adults: A Pilot Study. [PDF]
Spices were used as food preservatives prior to the advent of refrigeration, suggesting the possibility of effects on microbiota. Previous studies have shown prebiotic activities in animals and in vitro, but there has not been a demonstration of ...
Carpenter, Catherine L +11 more
core +1 more source

