Results 11 to 20 of about 1,501,016 (387)
The Lancet, 2005 Abstract Placebo, used here to mean an inert treatment given as if it was a real treatment, means lots of different things to different people. The structure of the article is that it begins by talking about the technical use of placebos in clinical trials, and the extent of the placebo response, then about the mechanism—“How does the ...
H J, McQuay, R A, Moore
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Journal of Clinical Oncology, 2020 PURPOSE In KEYNOTE-189, first-line pembrolizumab plus pemetrexed-platinum significantly improved overall survival (OS) and progression-free survival (PFS) compared with placebo plus pemetrexed-platinum in patients with metastatic nonsquamous non‒small ...
S. Gadgeel +25 more
semanticscholar +1 more source
Journal of Clinical Oncology, 2020 PURPOSE Pembrolizumab monotherapy has shown antitumor activity in patients with small-cell lung cancer (SCLC). The randomized, double-blind, phase III KEYNOTE-604 study compared pembrolizumab plus etoposide and platinum (EP) with placebo plus EP for ...
C. Rudin +20 more
semanticscholar +1 more source
When a placebo is not a ‘placebo’: a placebo effect on postprandial glycaemia [PDF]
British Journal of Clinical Pharmacology, 2007 What is already known about this subject • Although placebo effects have been shown on subjective continuous variables such as pain, placebo effects on objective continuous variables remain uncertain.• The present, pilot, follow‐up investigation represents the first to assess a placebo effect on the objective continuous measurement of acute ...
Vladimir Vuksan +3 more
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Mediterranean Journal of Clinical Psychology, 2022 Background: Nonadherence to homework assignments is a frequent problem among patients with depression during cognitive-behavioral therapy (CBT). The present study investigated the effects of two additional treatment components of CBT: a placebo and SMS ...
Nina Jurinec, Anne Schienle
doaj +1 more source
The effect of placebo and neurophysiological involvements [PDF]
, 2004 Placebo and placebo effect are important issues related to the drug therapy for clinical and scientific meanings. The rates of placebo may get as many as 50% for analgesic drugs in headache. The high answer to placebo brings questions on pathophysiology
Galli, Federica +2 more
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Trials, 2017 Background Placebo medications, by definition, are composed of inactive ingredients that have no physiological effect on symptoms. Nonetheless, administration of placebo in randomized controlled trials (RCTs) and in clinical settings has been ...
Sarah Ballou +12 more
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Sham Acupuncture Is Not Just a Placebo
Journal of Acupuncture & Meridian Studies, 2022 Sham acupuncture should have two distinct features: first, it must be morphologically similar to verum acupuncture for blinding purposes, and second, it must not exert physiologically expected effects of verum acupuncture.
Tae-Hun Kim +2 more
doaj +1 more source
The Ethics of Placebo-controlled Trials: Methodological Justifications [PDF]
, 2013 The use of placebo controls in clinical trials remains controversial. Ethical analysis and international ethical guidance permit the use of placebo controls in randomized trials when scientifically indicated in four cases: (1) when there is no proven ...
Grady, Christine, Millum, Joseph
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Tolerability, safety, and efficacy of adjunctive brivaracetam for focal seizures in older patients: A pooled analysis from three phase III studies [PDF]
, 2016 Introduction: This analysis was conducted to assess the tolerability, safety, and efficacy of brivaracetam (BRV) for adjunctive treatment of focal (partial-onset) seizures in patients aged ≥65 years.
Brodie, Martin J. +4 more
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