Results 201 to 210 of about 1,501,016 (387)

Mucosal‐associated invariant T cells in rheumatic diseases.

open access: yesArthritis &Rheumatology, Accepted Article.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor (TCR) and restriction by the MHC class I‐related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines. Upon activation, MAIT cells rapidly produce pro‐inflammatory cytokines,
Manon Lesturgie‐Talarek   +7 more
wiley   +1 more source

Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun   +19 more
wiley   +1 more source

Comparison of two doses of cimetidine and placebo in the treatment of duodenal ulcer: a multicentre trial. [PDF]

open access: bronze, 1979
Karna Dev Bardhan   +21 more
openalex   +1 more source

Peripheral blood gene expression profiling shows prognostic significance for the course of interstitial lung disease in systemic sclerosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective We used data from the placebo arm of the SENSCIS trial to determine the prognostic/predictive significance of peripheral blood cell (PBC) transcript modules for the course of forced vital capacity (FVC) in patients with systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) with and without mycophenolate mofetil (MMF) treatment ...
Shervin Assassi   +6 more
wiley   +1 more source

A Placebo-Controlled Double-Blind Crossover Investigation of the Side Effects Attributed to Oral Contraceptives

open access: bronze, 1971
Joseph W. Goldzieher   +4 more
openalex   +1 more source

Effect of Fremanezumab Compared With Placebo for Prevention of Episodic Migraine: A Randomized Clinical Trial

open access: yesJournal of the American Medical Association (JAMA), 2018
D. Dodick   +9 more
semanticscholar   +1 more source

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