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Placebo Analgesia: Cognition or Perception
Placebo analgesia has become a well-studied phenomenon that encompasses psychology, physiology and pharmacology. In this chapter we explore the complex interactions between these disciplines in order to argue that the placebo response is more than a simple change in perception but is a cognitive style driven by prior expectations.
Morton, Debora L +2 more
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A Voxel-Based Analysis of Neurobiological Mechanisms in Placebo Analgesia in Rats
NeuroImage, 2018Placebo analgesia is the beneficial effect that follows despite a pharmacologically inert treatment. Modern neuroimaging studies in humans have delineated the hierarchical brain regions involved in placebo analgesia.
Wei Yang, Yilong Cui, Yasuyoshi Watanabe
exaly +2 more sources
Cognitive and Emotional Factors in Placebo Analgesia
Journal of Psychosomatic Research, 2006Information that a painkiller has been administrated induces an expectancy of reduced pain, and the expectancy has been shown to reduce pain. This is termed placebo analgesia. We hypothesized that an expectancy of reduced pain reduces stress.The present study (N=84) investigated this hypothesis.
Magne Arve Flaten +2 more
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Placebo and Opioid Analgesia-- Imaging a Shared Neuronal Network [PDF]
It has been suggested that placebo analgesia involves both higher order cognitive networks and endogenous opioid systems. The rostral anterior cingulate cortex (rACC) and the brainstem are implicated in opioid analgesia, suggesting a similar role for ...
Predrag Petrović +2 more
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Neurological Sciences, 2006
The placebo effect is the effect that follows the administration of an inert treatment (the placebo), be it pharmacological or not. It is important to understand that a placebo procedure simulates a therapy through the surrounding psychosocial context.
Howard L. Fields, Donald D. Price
+6 more sources
The placebo effect is the effect that follows the administration of an inert treatment (the placebo), be it pharmacological or not. It is important to understand that a placebo procedure simulates a therapy through the surrounding psychosocial context.
Howard L. Fields, Donald D. Price
+6 more sources
Does active inference provide a comprehensive theory of placebo analgesia?
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2023Placebo interventions generate mismatches between expected pain and sensory signals from which pain states are inferred. Since we lack direct access to bodily states, we can only infer whether nociceptive activity indicates tissue damage or results from ...
C. Milde +2 more
semanticscholar +1 more source
Open-label nondeceptive placebo analgesia is blocked by the opioid antagonist naloxone.
Pain, 2022Open-label placebos, or placebos without deception, have been found to induce analgesia, a challenging concept that need to be investigated in detail.
F. Benedetti +3 more
semanticscholar +1 more source
Placebo analgesia and the heart
Pain, 2003Placebo-activated endogenous opioids act on pain mechanisms inducing analgesia, as well as on the respiratory centers inducing respiratory depression. Here, we show that placebo analgesia is accompanied by a reduced beta-adrenergic activity of the heart.
POLLO, Antonella +3 more
openaire +2 more sources

