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Neuroscience, 2020
Placebo analgesia has great potential to overcome the inadequacies of current drug therapies to treat conditions of chronic pain. The rostral ventromedial medulla (RVM) has been implicated as a critical relay in the antinociceptive pathway underpinning ...
Damien C. Boorman, K. Keay
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Placebo analgesia has great potential to overcome the inadequacies of current drug therapies to treat conditions of chronic pain. The rostral ventromedial medulla (RVM) has been implicated as a critical relay in the antinociceptive pathway underpinning ...
Damien C. Boorman, K. Keay
semanticscholar +1 more source
Placebo analgesia: a PET study
Experimental Brain Research, 2007Placebo analgesia involves complex mechanisms and sometimes has a marked effect on patients in pain. In this study we examined changes in regional cerebral blood flow (rCBF) under three different conditions (resting, hot, painful) before and after placebo administration using H(2)(15)O and positron emission tomography in ten healthy subjects.
Hidenori, Nemoto +4 more
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Placebo analgesia: Friend or foe?
Current Rheumatology Reports, 2006The magnitude of placebo analgesia is influenced by environmental and perceptual factors. Environmental factors include past exposure to effective analgesic agents and verbal suggestions and cues that foster a perception of being given an effective treatment.
Donald D, Price +2 more
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New insights into placebo analgesia
Current Opinion in Anaesthesiology, 2003The placebo effect is a widespread phenomenon in medicine, both in clinical trials and in routine medical practice. Most of our knowledge about the underlying psychological and physiological mechanisms comes from the study of placebo analgesia.When the correct methodological approach is used, striking placebo effects can be detected and these can be ...
BENEDETTI, Fabrizio +2 more
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The influence of reward sensitivity, heart rate dynamics and EEG‐delta activity on placebo analgesia
Behavioural Brain Research, 2019HighlightsA cold‐cup test served to induce cold‐pain for Pain and Placebo Analgesia conditions.Placebo, as compared to Pain treatment, was effective in pain and distress reduction.Time HRV & EEG‐delta loaded in the same factor in both pain and placebo ...
V. De Pascalis, Paolo Scacchia
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Placebo and Endogenous Mechanisms of Analgesia
2007The discovery of the endogenous systems of analgesia has produced a large amount of research aimed at investigating their biochemical and neurophysiological mechanisms and their neuroanatomical localization. Nevertheless, the neurobiological acquisitions on these mechanisms have not been paralleled by behavioural correlates in humans--in other words ...
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Mapping the anatomy of placebo analgesia
ScienceThe identification of somatotopy in brainstem pain modulatory pathways could help treat chronic ...
Massieh, Moayedi, Lauren Y, Atlas
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"HYPNOSIS," ANALGESIA, AND THE PLACEBO EFFECT
Journal of the American Medical Association, 1960Pain is a composite phenomenon, and not all aspects of pain are abolished by hypnosis. Subjects who report that they experience hypnotic analgesia or hypnotic hallucination are able to carry out a similar type of behavior without a hypnotic induction procedure. It has not been experimentally demonstrated that hypnotic procedures offer more satisfactory
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Preserved Capacity for Placebo Analgesia in the Elderly
The Journal of Pain, 2016The prevalence of chronic pain rises with increasing age. It has been suggested that the mechanisms responsible for the development of chronic pain overlap with mechanisms involved in aging, potentially implicating age-related changes in descending modulatory pathways.
Nathalie Wrobel +3 more
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