Brown adipose tissue and regulation of human body weight
Abstract Background Approximately 30% of the global population is affected by obesity. Traditional non‐surgical measures for weight loss have limited efficacy and tolerability. Therefore, there is a need for novel, effective therapies. Brown adipose tissue (BAT) has been implicated in physiological energy expenditure, indicating that it could be ...
Elissa Harb+5 more
wiley +1 more source
RESPONSE: Re: A Randomized, Placebo-Controlled Trial of Zoledronic Acid in Patients with Hormone-Refractory Metastatic Prostate Carcinoma [PDF]
Fred Saad
openalex +1 more source
Appraising the visibility, relevance and impacts of clinical pharmacology
Aims Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.
Serge Cremers+5 more
wiley +1 more source
We further developed the Dried Blood Spot (DBS) methodology for detection of four testosterone esters with focus on robustness and applicability in doping control. The study consisted of two parts: method development and validation, and a human administration study with intramuscular injections of 250 mg Sustanon® in healthy men.
Sara Amalie Solheim+6 more
wiley +1 more source
Correction to: Predictors of Placebo Response in Pharmacological Clinical Trials of Negative Symptoms in Schizophrenia: A Meta-regression Analysis. [PDF]
europepmc +1 more source
A Participant-Level Integrative Data Analysis of Differential Placebo Response for Suicidal Ideation and Nonsuicidal Depressive Symptoms in Clinical Trials of Intravenous Racemic Ketamine. [PDF]
Bloomfield-Clagett B+10 more
europepmc +1 more source
RESPONSE: Re: Double-Blind, Placebo-Controlled, Randomized Phase III Trial of Darbepoetin Alfa in Lung Cancer Patients Receiving Chemotherapy [PDF]
Johan F. Vansteenkiste, A. B. Colowick
openalex +1 more source
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan+3 more
wiley +1 more source
Towards a Sociology of Placebo Response: Body, Emotions, and Semiotics of Healing
With the emergence of the “sociology of body” and “sociology of emotions” in recent years, and the explosion of research about placebos and the mechanisms of their action, there is enough grounding now to consider the placebo response from a sociological
Shahram Rafieian
doaj