Results 211 to 220 of about 8,509,826 (346)

Brown adipose tissue and regulation of human body weight

open access: yesDiabetes/Metabolism Research and Reviews, Volume 39, Issue 1, January 2023., 2023
Abstract Background Approximately 30% of the global population is affected by obesity. Traditional non‐surgical measures for weight loss have limited efficacy and tolerability. Therefore, there is a need for novel, effective therapies. Brown adipose tissue (BAT) has been implicated in physiological energy expenditure, indicating that it could be ...
Elissa Harb   +5 more
wiley   +1 more source

Appraising the visibility, relevance and impacts of clinical pharmacology

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.
Serge Cremers   +5 more
wiley   +1 more source

Stability and detectability of testosterone esters in dried blood spots after intramuscular injections

open access: yesDrug Testing and Analysis, Volume 14, Issue 11-12, Page 1926-1937, November-December 2022., 2022
We further developed the Dried Blood Spot (DBS) methodology for detection of four testosterone esters with focus on robustness and applicability in doping control. The study consisted of two parts: method development and validation, and a human administration study with intramuscular injections of 250 mg Sustanon® in healthy men.
Sara Amalie Solheim   +6 more
wiley   +1 more source

A Participant-Level Integrative Data Analysis of Differential Placebo Response for Suicidal Ideation and Nonsuicidal Depressive Symptoms in Clinical Trials of Intravenous Racemic Ketamine. [PDF]

open access: yesInt J Neuropsychopharmacol, 2022
Bloomfield-Clagett B   +10 more
europepmc   +1 more source

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan   +3 more
wiley   +1 more source

Towards a Sociology of Placebo Response: Body, Emotions, and Semiotics of Healing

open access: yesInternational Journal of Body, Mind and Culture, 2014
With the emergence of the “sociology of body” and “sociology of emotions” in recent years, and the explosion of research about placebos and the mechanisms of their action, there is enough grounding now to consider the placebo response from a sociological
Shahram Rafieian
doaj  

Home - About - Disclaimer - Privacy