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Mechanisms of the placebo response
Pulmonary Pharmacology & Therapeutics, 2013The concept of placebo response has evolved in the past few years from the clinical trial setting and medical practice to a psychobiological model that gives us important information on how the patient's brain is modified by the psychosocial context around the therapy.
Fabrizio, Benedetti, Martina, Amanzio
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Placebo response, placebo effect, and two attributes
Psychopharmacology, 1979Two putative predictors of placebo response were studied in three samples of psychiatric outpatients. Two groups, 73 university medical center patients and 56 college health service patients, underwent 1 week of placebo treatment. A quasi-control group of 112 patients receiving no medication waited about 1 week before beginning psychotherapy.
D M, McNair +3 more
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Experimental Studies of the Placebo Response
Journal of Mental Science, 1960The critical evaluation of new drugs or remedies against inert substances or nonspecific procedures has led to the recognition that responses to a placebo are important in their own right. Such responses may be dramatic and persistent and they can be associated with quite definite physiological changes (Wolf and Pinsky, 1954).
J B, KNOWLES, C J, LUCAS
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Journal of Analytical Psychology, 2004
Abstract: Placebo effects contribute to beneficial therapeutic responses and are common in anxiety and depressive disorders. It is posited that placebo effects are yielded by autonomous feeling‐toned complexes capable of re‐establishing background self‐states of well‐being.
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Abstract: Placebo effects contribute to beneficial therapeutic responses and are common in anxiety and depressive disorders. It is posited that placebo effects are yielded by autonomous feeling‐toned complexes capable of re‐establishing background self‐states of well‐being.
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BMJ, 2008
If both subjective symptoms and physical signs of a physical disease respond to an inert process or substance, the patient did something that caused the response.1 If patients demonstrate this capacity to self treat, doctors should be asking at …
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If both subjective symptoms and physical signs of a physical disease respond to an inert process or substance, the patient did something that caused the response.1 If patients demonstrate this capacity to self treat, doctors should be asking at …
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Neurophysiology and psychobiology of the placebo response
Current Opinion in Psychiatry, 2008The placebo literature has substantially increased in 2006 and 2007, and more and more medical and psychological subspecialties have added empirical data to our knowledge.The theoretical framework of our understanding of the placebo response needs extension to account for findings that cannot be attributed to (Pavlovian) conditioning or suggestions ...
Sibylle, Klosterhalfen, Paul, Enck
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Behavioral factors in the placebo response
Neurological Sciences, 2011Given its presence in almost every clinical trial, the placebo is the most frequently studied substance in clinical research. Demonstration of treatment efficacy demands that the target (active) agent must be shown to be statistically significantly superior to an inert substance (placebo) not believed to be a specific therapy for the target condition ...
R E, Weeks, E, Newman
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Nursing Responsibility for the Placebo Effect
Journal of Medicine and Philosophy, 1991The placebo effect is a common phenomenon in therapy and research but has received very little attention as such in nursing research. This article reviews some of the literature which shows the placebo effect, which can be positive or negative, is a significant force.
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