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Placebos: A Review of The Placebo Response
American Journal of Gastroenterology, 2000Placebos have been a component of healing since the beginning. Whether consciously or unconsciously given, they are largely responsible for the success of medicine before randomized trials. Yet, even in this era of "evidence-based medicine," placebos remain enigmatic, and elicit mixed attitudes from divers disciplines.
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Placebo response, placebo effect, and two attributes
Psychopharmacology, 1979Two putative predictors of placebo response were studied in three samples of psychiatric outpatients. Two groups, 73 university medical center patients and 56 college health service patients, underwent 1 week of placebo treatment. A quasi-control group of 112 patients receiving no medication waited about 1 week before beginning psychotherapy.
D M, McNair +3 more
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Conditioned placebo responses.
Journal of Personality and Social Psychology, 1985Following earlier animal research, we attempt to condition placebo effects in human subjects. Four groups of 8 voluntary subjects were told that the experimenters would test a powerful new analgesic cream over three sessions by assessing its ability to reduce experimentally induced pain. The analgesic cream was, in fact, a placebo. In the first session
N J, Voudouris, C L, Peck, G, Coleman
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Journal of Analytical Psychology, 2004
Abstract: Placebo effects contribute to beneficial therapeutic responses and are common in anxiety and depressive disorders. It is posited that placebo effects are yielded by autonomous feeling‐toned complexes capable of re‐establishing background self‐states of well‐being.
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Abstract: Placebo effects contribute to beneficial therapeutic responses and are common in anxiety and depressive disorders. It is posited that placebo effects are yielded by autonomous feeling‐toned complexes capable of re‐establishing background self‐states of well‐being.
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Placebo Response in Schizophrenic Outpatients
Archives of General Psychiatry, 1960Introduction Placebo response has become a focus of much interest in psychiatric treatment. Not only have the values of the placebo in therapy and research been discussed, but its negative effects as well. Reports are present of placebos having emphatic adverse and structural effects on patients.
L D, HANKOFF +2 more
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Psychobiology of the placebo response
Autonomic Neuroscience, 2006The nature and determinants of the placebo response are widely unknown and are discussed controversially. This review presents a unifying concept for the understanding of the placebo response in clinical trials and practice based on three components: "Regression to the mean", "Pavlovian conditioning", and "Signal detection theory", and discusses the ...
Sibylle, Klosterhalfen, Paul, Enck
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Placebo responses in Parkinson's disease
2020Parkinson's disease (PD) patients exhibit strong placebo responses in clinical trials. Patient characteristics that affect placebo include patients' expectations of good outcomes, genetic variants, and personality. The presence of motor fluctuation and high baseline UPDRS motor scores predicted placebo response.
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