Results 1 to 10 of about 361,365 (49)
Effects of open-label placebos in clinical trials: a systematic review and meta-analysis
Scientific Reports, 2021 Open-label placebos (OLPs) are placebos without deception in the sense that patients know that they are receiving a placebo. The objective of our study is to systematically review and analyze the effect of OLPs in comparison to no treatment in clinical ...
Melina von Wernsdorff +3 more
semanticscholar +1 more source
Effects of Open-Label Placebos on State Anxiety and Glucocorticoid Stress Responses
Brain Science, 2021 Stress belongs to the most frequent negative feelings people are confronted with in daily life. Strategies against acute stress include, e.g., relaxation techniques or medications, but it is also known that placebos can successfully reduce negative ...
M. Schaefer, J. Hellmann-Regen, S. Enge
semanticscholar +1 more source
Placebos in clinical care: a suggestion beyond the evidence
Medical Journal of Australia, 2021 The clinical use of placebos is often justified by pointing to their important treatment effects. Proponents have also argued that the placebo effect can be amplified by manipulating the physical appearance of the pill,2 that placebo effects vary across ...
C. Maher +3 more
semanticscholar +1 more source
Placebos without deception reduce self-report and neural measures of emotional distress
Nature Communications, 2020 Several recent studies suggest that placebos administered without deception (i.e., non-deceptive placebos) can help people manage a variety of highly distressing clinical disorders and nonclinical impairments.
Darwin A. Guevarra +3 more
semanticscholar +1 more source
Open-label placebos for menopausal hot flushes: a randomized controlled trial
Scientific Reports, 2020 This study investigated the efficacy of an open-label placebo (OLP) treatment for menopausal hot flushes. Women with at least five moderate or severe hot flushes per day were allocated to receive four weeks of OLP for twice a day or no-treatment ...
Yiqi Pan +5 more
semanticscholar +1 more source
British Journal of Health Psychology, 2020 OBJECTIVE To examine how primary care physicians define placebo concepts, use placebos in clinical practice, and view open-label placebos (OLPs). DESIGN Semi-structured focus groups that were audio-recorded and content-coded. METHODS Two focus groups
Michael H Bernstein +8 more
semanticscholar +1 more source
Super Placebos: A Feasibility Study Combining Contextual Factors to Promote Placebo Effects
Frontiers in Psychiatry, 2020 Background: Ample evidence demonstrates that placebo effects are modulated by contextual factors. Few interventions, however, attempt to combine a broad range of these factors.
Jay A. Olson +3 more
semanticscholar +1 more source
Open label placebo: can honestly prescribed placebos evoke meaningful therapeutic benefits?
British medical journal, 2018 Results from small clinical trials suggesting that placebos can be ethically and effectively used in clinical practice warrant further study, argue Ted Kaptchuk and Franklin ...
T. Kaptchuk, F. Miller
semanticscholar +1 more source
BMC Psychiatry, 2020 Background The issue of unblinded outcome-assessors and patients has repeatedly been stressed as a flaw in allegedly double-blind antidepressant trials. Unblinding bias can for example result from a drug‘s marked side effects.
semanticscholar +1 more source
PLoS ONE, 2018 Background Several studies demonstrated that placebo treatment may have a significant impact on many different symptoms. While in the traditional view concealment of the placebo is essential, recent studies report intriguing evidence that placebos may ...
M. Schaefer +2 more
semanticscholar +1 more source