Results 1 to 10 of about 18,709 (258)

Effects of Open-Label Placebos on State Anxiety and Glucocorticoid Stress Responses

Brain Sciences, 2021
Stress belongs to the most frequent negative feelings people are confronted with in daily life. Strategies against acute stress include, e.g., relaxation techniques or medications, but it is also known that placebos can successfully reduce negative ...
Michael Schaefer, Julian Hellmann-Regen, Schaefer Michael   +2 more
exaly   +3 more sources

Roles of administration route, expectation, and belief in placebos in a randomized controlled trial with open-label placebos [PDF]

Scientific Reports
Recent reports challenge the view that placebos need to be given in deception. Numerous studies report remarkable effects when giving placebos honestly in an open way. However, the mechanisms of open-label placebos still remain to be cleared. For example,
Michael Schaefer, Carolin Liedtke, Sören Enge   +2 more
doaj   +2 more sources

Magnitude of the Digital Placebo Effect and Its Moderators on Generalized Anxiety Symptoms: Systematic Review and Meta-Analysis [PDF]

Journal of Medical Internet Research
Background Digital therapeutics (DTx) have attracted attention as the substitutes or add-ons to conventional pharmacotherapy. The number of clinical trials for DTx has increased recently, and one of the main targets for DTx is psychiatric disorders ...
Takashi Hosono, Rinka Tsutsumi, Yuki Niwa, Masuo Kondoh   +3 more
doaj   +2 more sources

Ethical challenges of placebo use in herbal medicine trials: multiple stakeholder perspectives from qualitative interviews [PDF]

BMC Medical Ethics
Background The ethical use of placebos in herbal medicine (HM) clinical trials remains contested, particularly in contexts where traditional medical systems shape patients’ beliefs and expectations.
Yixuan Li, Xuebin Zhang, Baoyun Qi, Jierong Gao, Xu Pang, Chi Zhang   +5 more
doaj   +2 more sources

Noble Humbug? Hard and soft laws on clinical placebo use [PDF]

Frontiers in Psychology
Despite the widespread historical and contemporary use of placebos in medicine, legal regulations addressing their administration remain limited in many countries.
Mélina Richard, Mélina Richard, Manuela Ganz, Lena Dominique Hornstein, Bohdan Stehlik, Mélanie Levy, Charlotte R. Blease, Marco Annoni, Bernice S. Elger, Jens Gaab   +9 more
doaj   +2 more sources

Placebo [PDF]

The Lancet, 2005
Abstract Placebo, used here to mean an inert treatment given as if it was a real treatment, means lots of different things to different people. The structure of the article is that it begins by talking about the technical use of placebos in clinical trials, and the extent of the placebo response, then about the mechanism—“How does the ...
H J, McQuay, R A, Moore
openaire   +4 more sources

A randomized controlled trial of effects of open-label placebo compared to double-blind placebo and treatment-as-usual on symptoms of allergic rhinitis

Scientific Reports, 2023
Placebo effects are known for numerous clinical symptoms. Until recently, deception of placebos was thought to be essential for placebo effects, but intriguing new studies suggest that even placebos without concealment (open-label placebos) may help ...
Michael Schaefer, Kurt Zimmermann, Paul Enck   +2 more
doaj   +1 more source

Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome

Frontiers in Pain Research, 2022
Background and Aims: Irritable bowel syndrome (IBS), a functional pain disorder of gut-brain interactions, is characterized by a high placebo response in randomized clinical trials (RCTs).
Rui-Sheng Wang, Rui-Sheng Wang, Anthony J. Lembo, Anthony J. Lembo, Ted J. Kaptchuk, Ted J. Kaptchuk, Vivian Cheng, Judy Nee, Judy Nee, Johanna Iturrino, Johanna Iturrino, Meenakshi Rao, Meenakshi Rao, Joseph Loscalzo, Joseph Loscalzo, Jocelyn A. Silvester, Jocelyn A. Silvester, Jocelyn A. Silvester, Jocelyn A. Silvester, Kathryn T. Hall, Kathryn T. Hall, Kathryn T. Hall   +21 more
doaj   +1 more source

Perception and practice of placebo use among physicians in Mangalore

Journal of Family Medicine and Primary Care, 2020
Background: Placebo use falls under two contexts: clinical care and research. In today's pharmacological era where treatment is available for almost all illnesses, there exists a lot of questions about the perceived efficacy and usage of placebos.
Ravinder Singh Aujla, Ritika Agarwal, Smriti Sinha, Avinash Kumar   +3 more
doaj   +1 more source

When and why placebo-prescribing is acceptable and unacceptable: a focus group study of patients' views. [PDF]

PLoS ONE, 2014
Surveys of doctors suggest that they use placebos and placebo effects clinically to help patients. However, patients' views are not well-understood.
Felicity L Bishop, Lizzi Aizlewood, Alison E M Adams   +2 more
doaj   +1 more source