Results 11 to 20 of about 22,441 (303)

Placebo use in the United kingdom: results from a national survey of primary care practitioners. [PDF]

open access: yesPLoS ONE, 2013
ObjectivesSurveys in various countries suggest 17% to 80% of doctors prescribe 'placebos' in routine practice, but prevalence of placebo use in UK primary care is unknown.MethodsWe administered a web-based questionnaire to a representative sample of UK ...
Jeremy Howick   +6 more
doaj   +2 more sources

Roles of administration route, expectation, and belief in placebos in a randomized controlled trial with open-label placebos [PDF]

open access: yesScientific Reports
Recent reports challenge the view that placebos need to be given in deception. Numerous studies report remarkable effects when giving placebos honestly in an open way. However, the mechanisms of open-label placebos still remain to be cleared. For example,
Michael Schaefer   +2 more
doaj   +2 more sources

Informed consent and placebo effects: a content analysis of information leaflets to identify what clinical trial participants are told about placebos. [PDF]

open access: yesPLoS ONE, 2012
BackgroundPlacebo groups are used in randomised clinical trials (RCTs) to control for placebo effects, which can be large. Participants in trials can misunderstand written information particularly regarding technical aspects of trial design such as ...
Felicity L Bishop   +3 more
doaj   +2 more sources

Ethical challenges of placebo use in herbal medicine trials: multiple stakeholder perspectives from qualitative interviews [PDF]

open access: yesBMC Medical Ethics
Background The ethical use of placebos in herbal medicine (HM) clinical trials remains contested, particularly in contexts where traditional medical systems shape patients’ beliefs and expectations.
Yixuan Li   +5 more
doaj   +2 more sources

Magnitude of the Digital Placebo Effect and Its Moderators on Generalized Anxiety Symptoms: Systematic Review and Meta-Analysis [PDF]

open access: yesJournal of Medical Internet Research
Background Digital therapeutics (DTx) have attracted attention as the substitutes or add-ons to conventional pharmacotherapy. The number of clinical trials for DTx has increased recently, and one of the main targets for DTx is psychiatric disorders ...
Takashi Hosono   +3 more
doaj   +2 more sources

Cancer and placebos [PDF]

open access: yesCa-A Cancer Journal for Clinicians, 1981
exaly   +3 more sources

Placebo [PDF]

open access: yesPostgraduate Medical Journal, 2005
Abstract Placebo, used here to mean an inert treatment given as if it was a real treatment, means lots of different things to different people. The structure of the article is that it begins by talking about the technical use of placebos in clinical trials, and the extent of the placebo response, then about the mechanism—“How does the ...
H J, McQuay, R A, Moore
openaire   +4 more sources

Effects of Open-Label Placebos on State Anxiety and Glucocorticoid Stress Responses

open access: yesBrain Sciences, 2021
Stress belongs to the most frequent negative feelings people are confronted with in daily life. Strategies against acute stress include, e.g., relaxation techniques or medications, but it is also known that placebos can successfully reduce negative ...
Michael Schaefer   +2 more
doaj   +1 more source

A randomized controlled trial of effects of open-label placebo compared to double-blind placebo and treatment-as-usual on symptoms of allergic rhinitis

open access: yesScientific Reports, 2023
Placebo effects are known for numerous clinical symptoms. Until recently, deception of placebos was thought to be essential for placebo effects, but intriguing new studies suggest that even placebos without concealment (open-label placebos) may help ...
Michael Schaefer   +2 more
doaj   +1 more source

Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome

open access: yesFrontiers in Pain Research, 2022
Background and Aims: Irritable bowel syndrome (IBS), a functional pain disorder of gut-brain interactions, is characterized by a high placebo response in randomized clinical trials (RCTs).
Rui-Sheng Wang   +21 more
doaj   +1 more source

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