Results 51 to 60 of about 553,015 (386)
Australian Journal of General Practice, 2019 BACKGROUND Placebo use is prevalent in primary care. A wealth of discourse on the ethical use of placebos in clinical contexts invariably assumes that placebos oblige practitioners to peddle in deception.
Charlotte R Blease
semanticscholar +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
The health economic potential of harnessing placebos in treatment of ADHD
European Psychiatry, 2021 Introduction Placebo research investigated the underlying mechanisms of placebo effects, but they are rarely used to optimize treatments. Ethical and legal concerns have been raised, but research demonstrated that placebo mechanisms can be used without
J. Hamberger +3 more
doaj +1 more source
Randomized placebo-controlled cross-over designs in clinical trials : a gold-standard to be reassessed [PDF]
, 2012 Placebo effects are well-known phenomena in medicine and biology. In fact, placebos are used as control conditions in randomized cross-over clinical trials to validate new treatments.
Goffaux P +3 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in Medicine, 2021 Introduction: Open-label placebos have been proposed as way of using long recognized analgesic placebo effects in an ethical manner. Recent evidence shows efficacy of open-label placebos for clinical conditions, but there is need for more research on ...
Dilan Sezer +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Investigación utilizando placebos
Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 2018 Se presenta un caso basado en un proyecto de investigación en dermatología, en el cual se compara una nueva propuesta terapéutica para el tratamiento con placebo de la onicomicosis.
José María Maya
doaj +3 more sources
BMC Medicine, 2023 Background Overtreatment poses a challenge to healthcare systems due to harmful consequences of avoidable side-effects and costs. This study presents the first account for examining the feasibility of placebo use for reducing overtreatment in primary ...
E. M. Krockow +4 more
doaj +1 more source
, 2018 The use of placebos in medicine is an area of ethical questioning, but we often do not consider the effect of placebos on daily life. One’s preconceptions on the outcomes of exercise physically affect health. Studies show being aware of the advantages of
Cupp, Kelsey
core +1 more source