Results 51 to 60 of about 488,286 (382)

Implementing placebo [PDF]

open access: yesBMJ, 2008
Pittrof and Rubinstein make the important point that the “placebo effect” is actually an effect—people often do get better on placebo.1 However, most, if not all, of the evidence for placebo effects comes from studies where patients expected to have a reasonable chance (generally 0.5) of receiving the active treatment.
openaire   +3 more sources

Open-Label Placebo Treatment for Acute Postoperative Pain (OLP-POP Study): Study Protocol of a Randomized Controlled Trial

open access: yesFrontiers in Medicine, 2021
Introduction: Open-label placebos have been proposed as way of using long recognized analgesic placebo effects in an ethical manner. Recent evidence shows efficacy of open-label placebos for clinical conditions, but there is need for more research on ...
Dilan Sezer   +10 more
doaj   +1 more source

PLACEBOES [PDF]

open access: yesSouthern Medical Journal, 1916
n ...
openaire   +1 more source

Evidencing general acceptability of open-label placebo use for tackling overtreatment in primary care: a mixed methods study

open access: yesBMC Medicine, 2023
Background Overtreatment poses a challenge to healthcare systems due to harmful consequences of avoidable side-effects and costs. This study presents the first account for examining the feasibility of placebo use for reducing overtreatment in primary ...
E. M. Krockow   +4 more
doaj   +1 more source

Randomized placebo-controlled cross-over designs in clinical trials : a gold-standard to be reassessed [PDF]

open access: yes, 2012
Placebo effects are well-known phenomena in medicine and biology. In fact, placebos are used as control conditions in randomized cross-over clinical trials to validate new treatments.
Goffaux P   +3 more
core   +2 more sources

Placebo Effect [PDF]

open access: yesThe Scientific World Journal, 2000
Nature and Science ran completely different news line-ups this week. But their lead stories agreed on one thing: patients matter. Nature led with a story about a group of patients who will share in a patent after giving blood and tissue samples to scientists.
openaire   +3 more sources

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

Deceptive and open-label placebo effects in experimentally induced guilt: a randomized controlled trial in healthy subjects

open access: yesScientific Reports, 2022
Placebos are known to yield significant effects in many conditions. We examined deceptive and open-label placebo effects on guilt, which is important for self-regulation and a symptom of mental disorders.
Dilan Sezer, Cosima Locher, Jens Gaab
doaj   +1 more source

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald   +74 more
wiley   +1 more source

Clinical efficacy of probiotic mouthwash in the treatment of gingivitis patients in Himachal population

open access: yesJournal of International Clinical Dental Research Organization, 2017
This study was conducted to analyze the changes in gingival health in patients treated with probiotic containing mouth rinse. Thirty volunteers between 20 and 35 years were randomly divided into two groups.
Vikas Jindal   +5 more
doaj   +1 more source

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