Results 51 to 60 of about 217,838 (342)

Optical Microfiber Biomedical Sensors: Classification, Applications, and Future Perspectives

Advanced Sensor Research, EarlyView.
This review delves deeply into the various types of optical microfiber biosensors, grounded firmly in their fundamental principles, and underscores their indispensable roles in pushing forward biomedical advancements. It examines the latest advancements, challenges faced by these biosensors in practical applications, future directions, breakthroughs ...
Lili Liang, Fei Xie, Li Jin, Bowen Yang, Li‐Peng Sun, Bai‐Ou Guan   +5 more
wiley   +1 more source

Antenatal Secondhand Smoke (SHS) Exposure and the Receptor for Advanced Glycation End-Products (RAGE)

Reproductive Medicine
Exposure to secondhand smoke (SHS) during fetal development results in negative postnatal effects, including altered organ development, changes in metabolism, and increased risk of respiratory illness.
Katrina L. Curtis, Kelsey M. Hirshi, Kary Tsai, Evan T. Clark, Brendan M. Stapley, Benjamin T. Bikman, Paul R. Reynolds, Juan Arroyo   +7 more
doaj   +1 more source

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

Advanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang, Zhinang Yin, Yanqiong Shen, Gang Feng, Fangfang Dai, Dongyong Yang, Zhimin Deng, Jing Yang, Ruizhi Chen, Leifeng Yang, Xian Chen, Qing Sun, Chunyu Huang, Yanxiang Cheng, Hongbing Deng, Lianghui Diao, Longfei Li, Tailang Yin   +17 more
wiley   +1 more source

Protocol to derive human trophoblast stem cells directly from primed pluripotent stem cells

STAR Protocols, 2022
Summary: Human trophoblast stem cells (hTSCs) are useful for studying human placenta development and diseases, but primed human pluripotent stem cells (hPSCs) routinely cultured in most laboratories do not support hTSC derivation.
Yanxing Wei, Lu Xiao, Lishi Ma, Zhijian Wang, Liping Huang, Huiying Li, Guangjin Pan, Stephen J. Lye, Yongli Shan   +8 more
doaj  

Epigenetics and the placenta [PDF]

Human Reproduction Update, 2010
The placenta is of utmost importance for intrauterine fetal development and growth. Deregulation of placentation can lead to adverse outcomes for both mother and fetus, e.g. gestational trophoblastic disease (GTD), pre-eclampsia and fetal growth retardation. A significant factor in placental development and function is epigenetic regulation.This review
Aafke P.A. van Montfoort, Johannes L.H. Evers, John C.M. Dumoulin, Ewka C.M. Nelissen   +3 more
openaire   +4 more sources

Genomic Insights into Post‐Domestication Expansion and Selection of Body Size in Ponies

Advanced Science, EarlyView.
The authors’ research delves into the history of ponies by assembling a pony genome and integrating horse genomes. This unveils genetic connections between Asian and European pony breeds. Cis‐regulatory elements of key genes impacting body size are also identified.
Xingzheng Li, Zihao Wang, Min Zhu, Binhu Wang, Shaohua Teng, Jing Yan, Haoyu Wang, Pengxiang Yuan, Shuwei Cao, Xiaolu Qu, Zhen Wang, Kai Zhan, Md. Panir Choudhury, Xintong Yang, Qi Bao, Sang He, Lei Liu, Pengju Zhao, Jicai Jiang, Hai Xiang, Lingzhao Fang, Zhonglin Tang, Yuying Liao, Guoqiang Yi   +23 more
wiley   +1 more source

Different Lengths of Gestational Exposure to Secondhand Smoke or e-Cigarette Vapor Induce the Development of Placental Disease Symptoms

Cells
Exposure to cigarette smoke is known to induce disease during pregnancy. Recent evidence showed that exposure to secondhand smoke (SHS) negatively impacts fetal and placental weights, leading to the development of intrauterine growth restriction (IUGR ...
Madison N. Kirkham, Christian Cooper, Emily Broberg, Peter Robertson, Derek Clarke, Brett E. Pickett, Benjamin Bikman, Paul R. Reynolds, Juan A. Arroyo   +8 more
doaj   +1 more source

Physiology and Pathophysiology of Steroid Biosynthesis, Transport and Metabolism in the Human Placenta

Frontiers in Pharmacology, 2018
The steroid hormones progestagens, estrogens, androgens, and glucocorticoids as well as their precursor cholesterol are required for successful establishment and maintenance of pregnancy and proper development of the fetus.
Waranya Chatuphonprasert, Waranya Chatuphonprasert, Kanokwan Jarukamjorn, Isabella Ellinger   +3 more
doaj   +1 more source

Resolution enhancement of placenta histological images using deep learning [PDF]

arXiv, 2022
In this study, a method has been developed to improve the resolution of histological human placenta images. For this purpose, a paired series of high- and low-resolution images have been collected to train a deep neural network model that can predict image residuals required to improve the resolution of the input images. A modified version of the U-net
arxiv  

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

Advanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu, Yaochang Wei, Yuelin Li, Yiming Dou, YongQiang Yang, Hanghang Liu, Xiaoyan Wang, Zheng Wang, Jianmin Su, Yong Zhang, Yongsheng Wang   +10 more
wiley   +1 more source