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Editorial: The placenta: the origin of chronic diseases in adults

open access: yesFrontiers in Endocrinology
Traditionally viewed as a temporary interface between mother and fetus, the placenta is currently recognized as a dynamic organ with far-reaching effects on the long-term health of the growing fetus. This organ mediates the exchange of nutrients, oxygen, and waste products, playing a pivotal role in fetal growth and development (1).
Fernanda R. Giachini   +4 more
doaj   +7 more sources

Advance in placenta drug delivery: concern for placenta-originated disease therapy

open access: yesDrug Delivery, 2023
In the therapy of placenta-originated diseases during pregnancy, the main challenges are fetal exposure to drugs, which can pass through the placenta and cause safety concerns for fetal development. The design of placenta-resident drug delivery system is
Miao Tang   +8 more
doaj   +4 more sources

A Review of Biomechanics Analysis of the Umbilical–Placenta System With Regards to Diseases

open access: yesFrontiers in Physiology, 2021
Placenta is an important organ that is crucial for both fetal and maternal health. Abnormalities of the placenta, such as during intrauterine growth restriction (IUGR) and pre-eclampsia (PE) are common, and an improved understanding of these diseases is ...
Shier Nee Saw   +2 more
doaj   +3 more sources

Three categories of similarities between the placenta and cancer that can aid cancer treatment: Cells, the microenvironment, and metabolites

open access: yesFrontiers in Oncology, 2022
Cancer is one of the most harmful diseases, while pregnancy is a common condition of females. Placenta is the most important organ for fetal growth, which has not been fully understand.
Huiyuan Pang   +7 more
doaj   +1 more source

Delayed diagnosis of intraplacental choriocarcinoma in a term healthy neonate—A case report and literature review

open access: yesClinical Case Reports, 2022
Gestational choriocarcinoma is rare. The intraplacental formation of choriocarcinoma is much rarer. We present a diagnosis of choriocarcinoma, 4 months postpartum, in a 28‐year‐old, presenting with vaginal bleeding.
Mahdokht Azizi   +3 more
doaj   +1 more source

Ten cases of Mycobacterium avium subsp. hominissuis infections linked to equine abortions in Japan, 2018–2019

open access: yesVeterinary Medicine and Science, 2021
Bacterial placentitis in horses commonly results in abortion, premature birth or compromised neonatal foal health. Although mycobacterial infections are generally uncommon in horses, 10 equine abortion cases caused by Mycobacterium avium subsp ...
Yuta Kinoshita   +5 more
doaj   +1 more source

Placenta Accreta Overlying a Caesarean Section Scar: A 10-Year Experience in a Tertiary-Care Centre in Portugal

open access: yesActa Médica Portuguesa, 2021
Introduction: Placenta accreta spectrum disorders are among the leading causes of maternal morbidity and mortality and their prevalence is likely to increase in the future.
Margarida Cal   +3 more
doaj   +1 more source

Development of Organ-on-Chip for the Study of Placental Pathologies: A Ten-Year Study of Literature Published

open access: yesHealth Technology Assessment in Action, 2023
Context: The placenta performs a crucial function in nutrient exchange, but studying this tissue poses a number of challenges. Utilizing microfluidic and microfabrication technologies, a 3D placenta-on-a-chip model provides a biomimetic alternative for ...
Ravindra Kalode, Pranoti Kalode
doaj   +1 more source

The placenta is the center of the chronic disease universe [PDF]

open access: yesAmerican Journal of Obstetrics and Gynecology, 2015
(Am J Obstet Gynecol 2015;213(suppl):S14–S20) This review article explores the potential role of the placenta in the development of chronic diseases later in life. It discusses studies reporting an inverse relationship between birthweight and chronic disease, leading to a better understanding of health and longevity in offspring.
Kent L, Thornburg, Nicole, Marshall
openaire   +2 more sources

Kidney–placenta crosstalk in health and disease

open access: yesClinical Kidney Journal, 2022
ABSTRACT Organ crosstalk allows the interaction between systems to adapt to a constant changing environment, maintaining homeostasis. The process of placentation and the new hormonal environment during pregnancy trigger physiological changes that modulate kidney function to control extracellular volume, acid–base balance and filtration ...
Cabarcas-Barbosa, Omar   +3 more
openaire   +2 more sources

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