Results 11 to 20 of about 2,454,543 (303)

Editorial: The placenta: the origin of chronic diseases in adults

open access: yesFrontiers in Endocrinology
Traditionally viewed as a temporary interface between mother and fetus, the placenta is currently recognized as a dynamic organ with far-reaching effects on the long-term health of the growing fetus. This organ mediates the exchange of nutrients, oxygen,
Fernanda R. Giachini   +4 more
doaj   +5 more sources

The placenta is the center of the chronic disease universe [PDF]

open access: yesAmerican Journal of Obstetrics and Gynecology, 2015
(Am J Obstet Gynecol 2015;213(suppl):S14–S20) This review article explores the potential role of the placenta in the development of chronic diseases later in life. It discusses studies reporting an inverse relationship between birthweight and chronic disease, leading to a better understanding of health and longevity in offspring.
Kent L, Thornburg, Nicole, Marshall
openaire   +2 more sources

Kidney–placenta crosstalk in health and disease

open access: yesClinical Kidney Journal, 2022
ABSTRACT Organ crosstalk allows the interaction between systems to adapt to a constant changing environment, maintaining homeostasis. The process of placentation and the new hormonal environment during pregnancy trigger physiological changes that modulate kidney function to control extracellular volume, acid–base balance and filtration ...
Cabarcas-Barbosa, Omar   +3 more
openaire   +2 more sources

Oxidative Stress in Placenta: Health and Diseases [PDF]

open access: yesBioMed Research International, 2015
During pregnancy, development of the placenta is interrelated with the oxygen concentration. Embryo development takes place in a low oxygen environment until the beginning of the second trimester when large amounts of oxygen are conveyed to meet the growth requirements. High metabolism and oxidative stress are common in the placenta. Reactive oxidative
Wu, Fan, Tian, Fu-Ju, Lin, Yi
openaire   +3 more sources

Notch Signaling Pathway and Human Placenta

open access: yesInternational Journal of Medical Sciences, 2012
Notch signaling was evolutionarily conserved and critical for cell-fate determination, differentiation and many other biological processes. Growing evidences suggested that Notch signaling pathway played an important role in the mammalian placental ...
Wei-Xiu Zhao, Jian-Hua Lin
doaj   +1 more source

The RNA landscape of the human placenta in health and disease [PDF]

open access: yesNature Communications, 2021
AbstractThe placenta is the interface between mother and fetus and inadequate function contributes to short and long-term ill-health. The placenta is absent from most large-scale RNA-Seq datasets. We therefore analyze long and small RNAs (~101 and 20 million reads per sample respectively) from 302 human placentas, including 94 cases of preeclampsia (PE)
Gong, Sungsam   +10 more
openaire   +5 more sources

Vaginal delivery through annular placenta – case report [PDF]

open access: yes, 2013
Annular placenta is an extremely rare morphological type of human placenta. It is commonly related to placental vessel abnormalities frequently causing antenatal and postnatal hemorrhage and operative delivery.
Živković, Nikica   +3 more
core   +1 more source

Is the Placenta Inflamed in Cardiovascular Disease?

open access: yesJACC: Advances, 2022
[Figure: see text]
Hameed, Afshan B., Licon, Ernesto
openaire   +2 more sources

Maternal psychosocial stress during pregnancy and placenta weight: evidence from a national cohort study [PDF]

open access: yes, 2010
To study in a large-scale cohort with prospective data the associations between psychosocial stress during pregnancy and placenta weight at birth. Animal data suggest that the placenta is involved in stress-related fetal programming.; We defined a priori
Andrea H Meyer   +21 more
core   +1 more source

Placental microRNAs: Responders to environmental chemicals and mediators of pathophysiology of the human placenta

open access: yesToxicology Reports, 2020
MicroRNAs (miRNAs) are epigenetic modifiers that play an important role in the regulation of the expression of genes across the genome. miRNAs are expressed in the placenta as well as other organs, and are involved in several biological processes ...
Kezia A. Addo   +4 more
doaj   +1 more source

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