Results 71 to 80 of about 255,775 (256)

Single‐cell and spatial transcriptomics: Discovery of human placental development and disease

FASEB BioAdvances
The human placenta is a vital organ, encompassing many distinct cell types, that maintains the growth and development of the fetus and is essential for substance exchange, defense, synthesis, and immunity.
Mi Tang, Liling Xiong, Jianghui Cai, Li Fan, Cheng Huang, Shimao Zhang, Ying Jin, Er‐dan Luo, ShaSha Xing, Xiao Yang   +9 more
doaj   +1 more source

Placenta: an old organ with new functions

Frontiers in Immunology
The transition from oviparity to viviparity and the establishment of feto-maternal communications introduced the placenta as the major anatomical site to provide nutrients, gases, and hormones to the developing fetus. The placenta has endocrine functions,
Sara Khorami-Sarvestani, Sara Khorami-Sarvestani, Negar Vanaki, Sorour Shojaeian, Kayhan Zarnani, Allan Stensballe, Allan Stensballe, Mahmood Jeddi-Tehrani, Amir-Hassan Zarnani, Amir-Hassan Zarnani   +9 more
doaj   +1 more source

The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]

, 2013
The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves, D'Herde, Katharina, Diez Fraile, Araceli, Lammens, Tim   +3 more
core   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Updates on placental studies in bitches [PDF]

Ciência Rural
: The placenta, despite being a temporary organ, is essential for the development and survival of the conceptus. During pregnancy, it performs essential functions, such as nutrition, protection, circulation, excretion, and secretion.
Sarah Fernanda Salgado Tavares Farias, Lúcia Daniel Machado da Silva   +1 more
doaj   +1 more source

Environmental contaminants exposure and preterm birth: a systematic review [PDF]

, 2019
Preterm birth is an obstetric condition associated with a high risk of infant mortality and morbidities in both the neonatal period and later in life, which has also a significant public health impact because it carries an important societal economic ...
Benedetti Panici, Pierluigi, MASCIULLO, LUISA, Piacenti, Ilaria, Porpora, Maria Grazia, Rech, Francesco, Scaramuzzino, Sara   +5 more
core   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

Advanced Science, EarlyView.
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie, Gulimire Yilihan, Qiong Chen, Dachuan Lin, Zhen Liu, Mengyi Yuan, Yujia Wang, Haoteng Xu, Weishang Zhou, Wanxin Gong, Yueer Li, Chen Peng, Tong Yang, Peng Gao, Qing Liu, Xin‐Hua Feng, Mu Xiao, Chao Jiang   +17 more
wiley   +1 more source

Giant chorioangioma of the complicated placenta with retroplacental hematoma. Presentation of a patient

Acta Médica del Centro, 2016
The abnormal proliferation of vessels derived from the placenta is known as chorioangioma, although it is the most common placental benign tumor not trophoblastic of the placenta occurs in a frequency as low as 1% of pregnancies.
Yarima Bravo Torres, Sandi Jiménez Puñales, Yoel Cardet Niebla   +2 more
doaj  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source