Results 61 to 70 of about 37,462 (251)

The 9+ month marathon: How pregnancy may have shaped human endurance capacities

open access: yesThe Anatomical Record, EarlyView.
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley   +1 more source

Developmental differences in cortical bone structure in chimpanzee and human femora reflect early locomotor independence in humans

open access: yesThe Anatomical Record, EarlyView.
Abstract The cortical bone structure of long bone diaphyses changes throughout growth via skeletal modeling and has important implications for bone strength and structural integrity. Ontogenetic trends in diaphyseal structure have been identified in both chimpanzees and humans but it is not yet clear how these trends compare given notable differences ...
Karen R. Swan   +3 more
wiley   +1 more source

Multidisciplinary Management of Ex Utero Intrapartum Treatment Procedure for a Large Cervical Mass—A Case Report and Review of Literature

open access: yesJournal of Obstetric Anaesthesia and Critical Care
Intrapartum management of babies with life-threatening airway obstruction is challenging and requires meticulous planning to achieve a positive outcome. The inability to maintain a patent airway after birth carries the risk of neonatal hypoxia leading to
Gita Nath   +3 more
doaj   +1 more source

Increased Risk of Intrahepatic Cholestasis of Pregnancy in Women With Systemic Lupus Erythematosus Exposed to Azathioprine

open access: yesArthritis &Rheumatology, EarlyView.
Objective To evaluate the risk of intrahepatic cholestasis of pregnancy (ICP) in azathioprine (AZA)–exposed versus unexposed systemic lupus erythematosus (SLE) pregnancies within the multicenter prospective Lupus in Pregnancy (LEGACY) cohort. Methods LEGACY is conducted at Systemic Lupus International Collaborating Clinics in Canada, South Korea, Peru,
Reem Farhat   +14 more
wiley   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

Microscopic detection of hemozoin in peripheral leukocytes fails to indicate plasmodial placental infection in pregnant women

open access: yesJournal of Infection in Developing Countries, 2017
Introduction: Malaria in pregnancy very often includes gestational (parasites in maternal peripheral blood) and placental (parasites in placental blood) infection, but the later condition can only be detected after delivery.
Carolina Lopez   +4 more
doaj   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

open access: yesBMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang   +13 more
wiley   +1 more source

Vaginal host–microbe signatures linked to placental outcomes in mares

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule   +7 more
wiley   +1 more source

INFLUENCE OF SOLUBLE PLACENTADERIVED FACTORS UPON EXPRESSION OF SURFACE RECEPTORS ON THP-1 CELLS

open access: yesМедицинская иммунология, 2014
. During the passage through the utero-placental circulation, peripheral blood monocytes are exposed to action of various soluble placenta-derived factors.
T. Yu. Lvova   +7 more
doaj   +1 more source

Wearable Ultrasound Patch for Autonomous and Continuous Fetal Monitoring

open access: yesFlexTech, EarlyView.
A wearable ultrasound patch enables autonomous, continuous fetal hemodynamic monitoring by combining deep‐tissue ultrasound hardware with real‐time vessel tracking, offering a new route for high‐risk pregnancy surveillance. ABSTRACT Ultrasonography is widely used for fetal monitoring but is limited to snapshot evaluations by trained sonographers ...
Enbo Xue, Binghao Wang
wiley   +1 more source

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