Results 81 to 90 of about 854,609 (354)

Thrombophilia in the pathogenesis of fetal growth retardation

Акушерство, гинекология и репродукция, 2021
Fetal growth retardation (FGR) is a complication of pregnancy that determines perinatal morbidity and mortality. It is a complex and multifaceted medical problem that does not lose its relevance.
E. A. Orudzhova, N. A. Samburova, E. V. Anichkova, K. E. Gotsiridze, V. O. Bitsadze   +4 more
doaj   +1 more source

Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]

, 2019
Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang, Fang-Hoover, June, Freed, Daniel C, Fu, Tong-Ming, Li, Fengsheng, Pereira, Lenore, Petitt, Matthew, Tabata, Takako, Wang, Dai   +8 more
core   +1 more source

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Causes and Consequences of the Dysregulated Maternal Renin-Angiotensin System in Preeclampsia

Frontiers in Endocrinology, 2019
A healthy pregnancy outcome depends on the activation of the renin-angiotensin-aldosterone system (RAAS) as a regulated, integrated response to the growing demands of the conceptus.
Eugenie R. Lumbers, Eugenie R. Lumbers, Eugenie R. Lumbers, Sarah J. Delforce, Sarah J. Delforce, Sarah J. Delforce, Anya L. Arthurs, Kirsty G. Pringle, Kirsty G. Pringle, Kirsty G. Pringle   +9 more
doaj   +1 more source

Doppler sonography of the uterine and the cubital arteries in normal pregnancies, preeclampsia and intrauterine growth restriction: evidence for a systemic vessel involvement [PDF]

, 2006
Aims: The decrease in uterine resistance during normal pregnancy is known to be related to invading trophoblast cells which derive from placental tissue. Uterine and peripheral resistance is elevated in preeclampsia.
Friese, Klaus, Jundt, Katharina, Kainer, Franz, Oberhoffer, Renate, Schiessl, Barbara   +4 more
core   +1 more source

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

Advanced Science, EarlyView.
Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain, Yao Gao, Sharmeen Islam, Li‐Wei Chen, Xinrui Li, Zhongyun Kou, Nathan C Law, Jeanene Marie de Avila, Mei‐Jun Zhu, Min Du   +9 more
wiley   +1 more source

Twin-twin transfusion syndrome: a literature review

Revista Médica de Minas Gerais, 2022
Twin-twin transfusion syndrome is a complication of monochorionic twin pregnancies. In addition to commonly occurring in the second trimester, it has high fetal and neonatal morbidity and mortality and incidence rates ranging from 10 to 15% among all ...
Marcio Erlei Vieira de Sa Filho, Rafael Lauro Silva Lima, Fredson Guilherme Gomes   +2 more
doaj  

Activity of kallikrein-kinin system of blood and state of placental circulation at full-term pregnancy

Бюллетень сибирской медицины, 2012
The activity of kallikrein-kinin system of blood and the state of placental circulation at full-term physiological pregnancy have been studied.In 30 pregnant women aged 18—27 at 38th—40th weeks of pregnancy, the activity of  kallikrein-kinin system (KKS)
G. T. Kairov, V. S. Denisova, M. A. Medvedev   +2 more
doaj   +1 more source

Features of the formation of pathogenetic changes of the placental complex on the background of intra-uteronomy infection

Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2022
. One of the main complications during early embryogenesis and placentation is placental insufficiency. Under the influence of various factors, namely infectious factors, which, depending on the biological specificity, negatively affect the germ cells of
Alisa Hoshovska
doaj   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source