Results 51 to 60 of about 24,941 (289)

Lack of placental neurosteroid alters cortical development and female somatosensory function

Frontiers in Endocrinology, 2022
Placental endocrine function is essential to fetal brain development. Placental hormones include neurosteroids such as allopregnanolone (ALLO), a regulator of neurodevelopmental processes via positive allosteric modulation of the GABAA receptor (GABAA-R).
Dana Bakalar, Jiaqi J. O’Reilly, Helene Lacaille, Jacquelyn Salzbank, Jacob Ellegood, Jason P. Lerch, Toru Sasaki, Yuka Imamura, Kazue Hashimoto-Torii, Claire-Marie Vacher, Anna A. Penn   +10 more
doaj   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Novel use of proton magnetic resonance spectroscopy (1HMRS) to non-invasively assess placental metabolism.

PLoS ONE, 2012
BackgroundPlacental insufficiency is a major cause of antepartum stillbirth and fetal growth restriction (FGR). In affected pregnancies, delivery is expedited when the risks of ongoing pregnancy outweigh those of prematurity.
Fiona C Denison, Scott I Semple, Sarah J Stock, Jane Walker, Ian Marshall, Jane E Norman   +5 more
doaj   +1 more source

Examination of the inflammatory nature of different placental syncytiotrophoblast microparticles (STBM) preparations on human monocytes [PDF]

, 2009
Background: Healthy human pregnancies are accompanied by a mild systemic maternal inflammatory response, which includes activation of peripheral blood monocytes.
Messerli, Marianne Simone
core   +1 more source

Canine brachycephalic obstructive airway syndrome as a model for studying the effects of obstructive sleep apnea during pregnancy

Animal Models and Experimental Medicine, EarlyView.
We observed a negative effect of brachycephalic obstructive airway syndrome (BOAS) in a staggered manner based on the severity of the condition on respiratory and cardiac patterns, glycemia, acid–base balance, fetal growth, and uterine artery hemodynamics, thus requiring adaptations within the fetal–placental unit. Severely affected bitches had uterine
Roberto Rodrigues da Rosa Filho, Thayná Pantoja Gardés, Maíra Morales Brito, Leticia Lima de Almeida, Camila Infantosi Vannucchi   +4 more
wiley   +1 more source

ROLE OF ANGIOGENIC FACTORS FOR TRANSPLACENTAL TRANSFER OF THE MEASLES ANTIBODIES

Медицинская иммунология, 2019
Angiogenesis factors (VEGF, Ang-1, TGF-β) influence production, development and functioning of vascular endothelium that are part of the placental barrier structure and are involved into transplacental transfer of different substances.
A. D. Shmitko, M. P. Kostinov, V. B. Polyschuk, A. A. Savisko, G. V. Vasilieva   +4 more
doaj   +1 more source

Ontogeny of murine bony semicircular canal form

The Anatomical Record, EarlyView.
Abstract The labyrinthine geometry and functional anatomy of the semicircular canals have intrigued scientists for decades, and there has been considerable interest in understanding how these complex structures grow and develop with evidence emerging from human studies that size maturation occurs exceptionally early by comparison with other systems ...
Marcela Cárdenas‐Serna, Nathan Jeffery   +1 more
wiley   +1 more source

Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice

The Anatomical Record, EarlyView.
Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore, Madeline Tourigny, Diana Quinonez, Kevin Barr, Matthew W. Grol, Katherine E. Willmore   +5 more
wiley   +1 more source

Twin pregnancies and the limits of the energetics of gestation and growth hypothesis

The Anatomical Record, EarlyView.
Abstract The “Energetics of Gestation and Growth” (EGG) hypothesis proposes that human birth timing and the associated secondary altriciality of human newborns is determined by limits in maternal metabolic capacity. According to this model, labor is triggered when the increasing fetal energy requirements exceed the expectant mother's maximum sustained ...
Cédric Cordey, Nicole M. Webb, Martin Haeusler   +2 more
wiley   +1 more source

THE ROLE OF CYTOKINES AND AGMATINE IN THE DEVELOPING PLACENTA WITH PHYSIOLOGICAL AND PREGNANCY COMPLICATED

Медицинский вестник Юга России, 2013
Purpose: To study the content of cytokines and agmatine in the development of the placenta in physiological and complicated gestation.Materials and Methods: 57 women, of which 34 women with physiological pregnancy and 23 women with placental ...
A. S. Degtyareva, I. I. Krukier, E. V. Narezhnaya, V. V. Avrutskaya, M. A. Levkovich, A. A. Nikashina   +5 more
doaj   +1 more source