Results 91 to 100 of about 10,458 (283)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Fully embedded optical and electrical interconnections in flexible foils [PDF]
, 2009 This paper presents the development of a technology platform for the full integration of opto-electronic and electronic components, as well as optical interconnections in a flexible foil. A technology is developed to embed ultra thin (20 μ m) VCSEL's and
Bosman, Erwin +4 more
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Dzheltulak system of the Oktyabrsky ore-placer node of the Amur gold-bearing province
Известия высших учебных заведений: Геология и разведкаBackground. Information on the Dzheltulak large placer system of the Amur gold-bearing province, which has produced 80 tons of gold, is presented. Aim. To determine the geological and structural position of the Dzheltulak placer system, one of the most ...
V. A. Stepanov, A. V. Melnikov
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Auriferous Tertiary Gravels Near Rocker, in Silver Bow County, Montana [PDF]
, 1934 Between the villages of Rocker and Silver Bow, in southwestern Montana, are found an interesting group of placers. Gold occurs in Tertiary gravel beds that are interstratified with beds of rhyolitic volcanic ash.
McLaughlin, William C.
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Russian Journal of Earth SciencesThe article is dedicated to estimation of tertiary terrigenous strata role in world gold mining. Localization peculiarities of tertiary gold deposits and their placers were examined.
Vladimirceva Ol'ga +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Technological research of process for producing titanium rich slag and complex titanium-containing ferroalloy. [PDF]
Heliyon, 2023 Vorobkalo N +4 more
europepmc +1 more source
European REE resources: alkaline magmatism and beyond [PDF]
, 2015 Europe has resources of many of the critical metals, pa rticularly the rare earth el ements (REE); yet economic, environmental and accessibility issues have combined to slow progress toward the explo itation of these resources.
Deady, E.A. +2 more
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