Results 91 to 100 of about 305,652 (296)
Recibido 22 de marzo de 2010 • Aceptado 24 de junio de 2010 • Corregido 06 de julio de 2010 La evolución de una educación centrada en la enseñanza, a una perspectiva de aprendizaje, constituye un cambio de paradigma, así lo afirma la autora de este artículo, quien invita a asumir el placer de aprender como dinamizador de la construcción ...
openaire +4 more sources
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
A STUDY OF THE CHANGES TAKING PLACE IN WHISKEY STORED IN WOOD. [PDF]
C. A. Crampton, L. M. Tolman
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
OBSERVATIONS ON THE CHANGES WHICH TAKE PLACE IN THE PUPIL AFTER DEATH, AND THE ACTION OF ATROPINE AND OTHER ALKALOIDS ON THE DEAD EYE. [PDF]
J N Marshall
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Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
SEASHORE AND OFFSHORE AMBERSUCCINITE PLACERS IN UKRAINE
The article speaks about the key influence of the sea basin on the formation of ambersuccinite as a mineral and its deposits as the first intermediate collectors.
Victor Matsui, Uliana Naumenko
doaj +1 more source
The validity of the microchemical test for the oxygen place in tissues [PDF]
A. N. Drury
openalex +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Construction Accidents in Spain: Implications for an Aging Workforce. [PDF]
Fontaneda I +3 more
europepmc +1 more source

