Two intracellular and cell type-specific bacterial symbionts in the placozoan Trichoplax H2
Placozoa is an enigmatic phylum of simple, microscopic, marine metazoans(1,2). Although intracellular bacteria have been found in all members of this phylum, almost nothing is known about their identity, location and interactions with their host(3-6). We
Dubilier, N.+7 more
core +1 more source
Genetic, structural, and molecular insights into the function of ras of complex proteins domains [PDF]
Ras of complex proteins (ROC) domains were identified in 2003 as GTP binding modules in large multidomain proteins from Dictyostelium discoideum. Research into the function of these domains exploded with their identification in a number of proteins ...
Civiero, Laura+3 more
core +2 more sources
Phylogenetic Relationships within the Opisthokonta Based on Phylogenomic Analyses of Conserved Single-Copy Protein Domains [PDF]
Many of the eukaryotic phylogenomic analyses published to date were based on alignments of hundreds to thousands of genes. Frequently, in such analyses, the most realistic evolutionary models currently available are often used to minimize the impact of ...
A. J. Roger+61 more
core +1 more source
New genomic data and analyses challenge the traditional vision of animal epithelium evolution
Background The emergence of epithelia was the foundation of metazoan expansion. Epithelial tissues are a hallmark of metazoans deeply rooted in the evolution of their complex developmental morphogenesis processes.
Hassiba Belahbib+6 more
doaj +1 more source
The phylogenetic position of ctenophores and the origin(s) of nervous systems [PDF]
Ctenophores have traditionally been treated as eumetazoans, but some recent whole genome studies have revived the idea that they are, rather, the sister group to all other metazoans.
Jákely, Gáspár+2 more
core +3 more sources
Reply to Halanych et al.: Ctenophore misplacement is corroborated by independent datasets [PDF]
In their letter, Halanych et al. (1) criticize our recent assertion (2) that the phylogenetic placement of ctenophores as the sister group to all other animals (the Ctenophora-sister hypothesis) in three previous studies (3–5) was an artifact caused by ...
Dohrmann, Martin+7 more
core +4 more sources
Let’s end taxonomic blank slates with molecular morphology
Many known evolutionary lineages have yet to be described formally due to a lack of traditional morphological characters. This is true for genetically distinctive groups within the amoeboid Placozoa animals, the protists in ponds, and the bacteria that ...
Michael Tessler+8 more
doaj +1 more source
A pre-metazoan origin of the CRK gene family and co-opted signaling network. [PDF]
CRK and CRKL adapter proteins play essential roles in development and cancer through their SRC homology 2 and 3 (SH2 and SH3) domains. To gain insight into the origin of their shared functions, we have investigated their evolutionary history.
Akira IMAMOTO+25 more
core +2 more sources
Our study looks at the association between microRNA expression and disease resistance in Caribbean staghorn corals infected with White Band Disease. We find three microRNAs differentially expressed due to disease resistance with putative targets involved in innate immunity.
Brecia A. Despard+3 more
wiley +1 more source
Identification, distribution and molecular evolution of the pacifastin gene family in Metazoa
Background Members of the pacifastin family are serine peptidase inhibitors, most of which are produced as multi domain precursor proteins. Structural and biochemical characteristics of insect pacifastin-like peptides have been studied intensively, but ...
Van Soest Sofie+4 more
doaj +1 more source