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Yersinia pestis: the Natural History of Plague

open access: yesClinical Microbiology Reviews, 2020
The Gram-negative bacterium Yersinia pestis is responsible for deadly plague, a zoonotic disease established in stable foci in the Americas, Africa, and Eurasia. Its persistence in the environment relies on the subtle balance between Y.
Didier Raoult, Michel Drancourt
exaly   +2 more sources

Antimicrobial Treatment and Prophylaxis of Plague: Recommendations for Naturally Acquired Infections and Bioterrorism Response

open access: yesMMWR Recommendations and Reports, 2021
Summary This report provides CDC recommendations to U.S. health care providers regarding treatment, pre-exposure prophylaxis, and postexposure prophylaxis of plague.
Christina A Nelson, Shannon Fleck
exaly   +2 more sources

Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics

open access: yesGenes and Immunity, 2019
Plague is a vector-borne disease caused by Yersinia pestis. Transmitted by fleas from rodent reservoirs, Y. pestis emerged
Christian E Demeure   +2 more
exaly   +3 more sources

FPR1 is the plague receptor on host immune cells

open access: yesNature, 2019
The causative agent of plague, Yersinia pestis, uses a type III secretion system to selectively destroy immune cells in humans, thus enabling Y. pestis to reproduce in the bloodstream and be transmitted to new hosts through fleabites.
Patrick Osei-Owusu   +2 more
exaly   +2 more sources

Analysis of 3800-year-old Yersinia pestis genomes suggests Bronze Age origin for bubonic plague

open access: yesNature Communications, 2018
The origin of Yersinia pestis and the early stages of its evolution are fundamental subjects of investigation given its high virulence and mortality that resulted from past pandemics. Although the earliest evidence of Y.
Maria A Spyrou, Rezeda I Tukhbatova
exaly   +2 more sources

Stone Age Yersinia pestis genomes shed light on the early evolution, diversity, and ecology of plague

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2022
Significance The bacterium Yersinia pestis has caused numerous historically documented outbreaks of plague and research using ancient DNA could demonstrate that it already affected human populations during the Neolithic.
Aida Andrades Valtueña   +48 more
semanticscholar   +1 more source

Lessons Learned from and Prospects of Using Mobile Laboratories for Epidemiological Surveillance over Plague, Other Particularly Dangerous, Natural-Focal, Zoonotic Infectious Diseases

open access: yesПроблемы особо опасных инфекций, 2021
The review presents the materials on the use of mobile laboratories, developed in the Russian Federation, in the framework of four main areas: monitoring of territories to identify the circulation of pathogens of natural-focal infectious diseases ...
I. N. Sharova   +20 more
doaj   +1 more source

No evidence for persistent natural plague reservoirs in historical and modern Europe

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2022
Significance Plague killed millions of people during the three pandemics in the past two millennia. Despite much research, it remains unclear whether persistent natural plague reservoirs existed in Europe.
N. Stenseth   +18 more
semanticscholar   +1 more source

Epidemiological Characteristics of Human and Animal Plague in Yunnan Province, China, 1950 to 2020

open access: yesMicrobiology Spectrum, 2022
This study analyzed the epidemiological characteristics of 3,464 human plague cases and the distribution pattern of 4,968 Yersinia pestis isolates from humans, hosts, and vector insects from 1950 to 2020 among two natural plague foci in Yunnan Province ...
Haonan Han   +14 more
doaj   +1 more source

Plague. [PDF]

open access: yesTropical diseases bulletin, 1998
Yersinia pestis, the aetiological agent of plague, has in the past caused social devastation on a scale unmatched by other infectious diseases. There is still a public health problem from plague, with at least 2000 cases reported annually. Most of these cases are of the bubonic form.
R W, Titball, S E, Leary
openaire   +12 more sources

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