Results 41 to 50 of about 10,215 (209)

Enhancement of the Technology for Live Tularemia Vaccine Production

Проблемы особо опасных инфекций, 2016
Objective of the study was to develop and test new biotechnological approaches for live tularemia vaccine production.Materials and methods: Francisella tularensis 15 NIIEG strain was used as producer-strain; Francisella tularensis 503 strain – as test ...
O. A. Volokh, A. V. Komissarov, M. V. Antonycheva, O. A. Lobovikova, N. G. Avdeeva, N. I. Vakhrushina, N. P. Mironova, D. N. Bibikov, A. K. Nikiforov   +8 more
doaj   +1 more source

Experimental Preventive Anti-Tularemia Preparation

Проблемы особо опасных инфекций, 2013
Designed is an experimental preparation of a prototype chemical tularemia vaccine (PCTV). It is composed of protective antigenic complex (PAC) of tularemia microbe and S-layer protein (Slp) of plague microbe.
O. A. Volokh, E. M. Kuznetsova, E. A. Smol’Kova, T. N. Shchukovskaya, S. A. Bugorkova, N. G. Avdeeva, D. G. Filimonova, T. P. Shmel’Kova, S. N. Klyueva, A. K. Nikiforov   +9 more
doaj   +1 more source

Metatranscriptomics reveal differences in in situ energy and nitrogen metabolism among hydrothermal vent snail symbionts [PDF]

, 2013
Despite the ubiquity of chemoautotrophic symbioses at hydrothermal vents, our understanding of the influence of environmental chemistry on symbiont metabolism is limited. Transcriptomic analyses are useful for linking physiological poise to environmental
Beinart, R. A., Delong, Edward, DeLong, Edward Francis, Girguis, P. R., Sanders, J. G., Stewart, F. J.   +5 more
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Occurrence of Genetic Determinants Associated with Attenuation in Wild-Type Strains of the Tularemia Microbe

Проблемы особо опасных инфекций
The aim of our work was to determine genetic markers associated with attenuation (deletions in RD-18, RD-19 positions, single mutations) in natural strains of the causative agent of tularemia. Materials and methods.
E. A. Naryshkina, N. A. Osina, S. D. Katyshev, Ya. M. Krasnov, N. A. Sharapova, A. V. Fedorov, A. D. Katyshev, O. Yu. Lyashova, A. V. Osin, Z. L. Devdariani, S. A. Shcherbakova   +10 more
doaj   +1 more source

Methods and Technologies of Cholera Vibrio Cultivation (Scientific Review)

Проблемы особо опасных инфекций, 2013
Displayed is the review of domestic and foreign literature sources devoted to matters of cholera vibrio cultivation. Discussed is the information concerning the following methods utilized in the technological process of vibrio growth stimulation: batch ...
S. A. Eremin, Yu. A. Aleshina, A. V. Komissarov, O. V. Gromova, Yu. G. Vasin, A. K. Nikiforov, L. F. Livanova, O. A. Volokh, O. A. Lobovikova, V. S. Bronnikova   +9 more
doaj   +1 more source

Production of Lyophilized Preparation of Anti-Rabies Immunoglobulin and Examination of Its Main Properties

Проблемы особо опасных инфекций, 2011
Presented are data on examination of physical, chemical and biological characteristics of lyophilized preparation of geterologous anti-rabies immunoglobulin. Dry and original liquid forms of immunoglobulin were comparatively analyzed.
E. G. Abramova, N. N. Kochkalova, A. K. Nikiforov, A. Yu. Butyrskii, Yu. V. Ivanov, N. V. Sinitsyna, T. A. Mikheeva, L. N. Minaeva, M. V. Galkina, L. V. Savitskaya, S. V. Generalov, M. N. Kireev, N. A. Sharapova   +12 more
doaj   +1 more source

Electro-Optical Analysis of Cell Viability of Tularemia Microbe Vaccine Strain

Проблемы особо опасных инфекций, 2020
Objective: to study the possibility of applying electro-optical analysis for the assessment of cell viability of tularemia microbe vaccine strain at different stages of experimental live tularemia vaccine production.Materials and methods.
O. A. Volokh, S. V. Borisova, D. N. Bibikov, E. M. Kuznetsova, Yu. I. Samokhvalova, N. G. Avdeeva, A. V. Komissarov, A. K. Nikiforov   +7 more
doaj   +1 more source

Comparative Study of Some Physical-Chemical and Immunochemical Properties of Plague Microbe Lipopolysaccharide Preparations Obtained with the Help of Different Techniques

Проблемы особо опасных инфекций, 2012
, and degraded polysaccharide (PS) are easily soluble in water and in 0,9 % NaCl solution. They are homogenous and characterized by an adequate degree of purity.
T. A. Polunina, N. P. Guseva, M. N. Kireev, T. M. Taranenko, Z. L. Devdariani, S. P. Zadnova, E. M. Kuznetsova, A. V. Stepanov, S. N. Klyueva, T. L. Zakharova   +9 more
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Phylogenetic History of Kara Kum Desert Focus

Проблемы особо опасных инфекций, 2020
Objective of the study was to analyze phylogenetic relation of the strains and dissemination routes of Yersinia pestis in Kara Kum desert focus in XX century.Materials and methods.
G. A. Eroshenko, L. M. Kukleva, Zh. V. Al’khova, A. N. Balykova, N. V. Popov, Ya. M. Krasnov, N. S. Chervyakova, V. V. Kutyrev   +7 more
doaj   +1 more source

Results of Modeling Experiments in Designing Immuno-Enzyme Test-System for the Detection of Antibodies to Yersinia pestis F1 (ELISA-Ab-F1 Yersinia pestis)

Проблемы особо опасных инфекций, 2013
Designed is immuno-enzyme test-system for the detection of antibodies to Yersinia pestis capsular antigen F1 – “ELISA-Ab-F1 Yersinia pestis”.
Z. L. Devdariani, N. E. Tereshkina, T. M. Taranenko, M. N. Kireev, I. V. Terekhova, G. V. Grigor’Eva, M. N. Islyaeva, N. M. Ermakov, N. A. Vinogradova, A. N. Malakhaeva   +9 more
doaj   +1 more source