Results 61 to 70 of about 742,078 (274)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Co-design, implementation, and evaluation of plain language genomic test reports

open access: yesnpj Genomic Medicine, 2022
Understanding and communicating genomic results can be challenging for families and health professionals without genetic specialty training. Unlike modifying existing laboratory reports, plain language genomic test reports provide an opportunity for ...
Gemma R. Brett   +8 more
doaj   +1 more source

Burying Evidence\u27s Dead Hand [PDF]

open access: yes, 2019
When the Rhode Island Rules of Evidence were adopted, they displaced all inconsistent case law existing at the time. Though the Rules retain a great deal of the evidence practice that preceded them, there is much in evidence practice that changed with ...
Provencher, Matthew D.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Plain English Movement, The Plain English Movement: Panel Discussion [PDF]

open access: yes, 1981
One of the dominant events between 1975 and today in United States consumer law was the birth of what has become known as the plain English movement . For centuries lawyers have been derided for the nature of their prose.
Felsenfeld, Carl
core   +1 more source

Recursive Neural Networks Can Learn Logical Semantics [PDF]

open access: yes, 2015
Tree-structured recursive neural networks (TreeRNNs) for sentence meaning have been successful for many applications, but it remains an open question whether the fixed-length representations that they learn can support tasks as demanding as logical ...
Bowman, Samuel R.   +2 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Using Plain Language to Simplify Complex Legal Terms in the Banking Sector: The Case for African Languages in the South African Banks

open access: yesInternational Journal of Applied Research in Business and Management
Plain language refers to the use of understandable language in consumer documents. This is done to prevent practices wherein vulnerable consumers enter into agreements with banks while they do not fully understand the content and consequences of the ...
Menzi Zamokwakhe Thango
doaj   +1 more source

The Ethics of Plain Language: A Technical Communicator\u27s Perspective [PDF]

open access: yes, 2016
I appreciate the opportunity to write to lawyers about the ethics of plain language from a technical-communication perspective. I am a professor of technical communication and, formerly, a full-time technical writer. In this article, I’ll view the ethics
Willerton, Russell
core   +1 more source

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