Results 81 to 90 of about 91,797 (279)
Em QuestãoInformation Design is essential for enhancing the accessibility and comprehension of complex health information, particularly in women’s health, where specialized terminology and sensitive content require strategies that make knowledge understandable and
Isabela Correa Macena +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
i-comDesigning writing support tools is challenging because writing is a complex, open-ended task with different target groups. This paper explores how software can help writers make texts more understandable for people with cognitive impairments.
Heuer Hendrik +2 more
doaj +1 more source
Improving readability of informed consents for research at an academic medical institution
Journal of Clinical and Translational Science, 2017 IntroductionThe final rule for the protection of human subjects requires that informed consent be “in language understandable to the subject” and mandates that “the informed consent must be organized in such a way that facilitates comprehension.” This ...
Kristie B. Hadden +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Returning aggregate results of clinical trials: Empirical data of patient preferences
Journal of Clinical and Translational Science, 2018 Introduction:The purpose of this research was to understand the preferences of patients receiving integrative medicine services for return of aggregate study results.Methods:A brief online survey (survey 1) was sent to 341 cancer patients receiving ...
Carmen E. Aldinger +4 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Plain English in Legal Language: A Comparative Study of Two UK Acts of Parliament
, 2015 The history of England has left its mark on legal English, a language for specific purposes well known for its complexity and conservatism throughout the world, thanks to the widespread reach of the British Empire. According to many scholars, today legal
Riera, Catalina
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The Problem of Textual Engagement in Gerontolinguistics
Ученые записки Казанского университета: Серия Гуманитарные наукиIncreasing life expectancy has led to a marked growth in the older population with cognitive deficits. This study examines how institutional texts match the communication skills of older people with accelerated aging phenotype. Major shifts in the speech
N. G. Burmakina
doaj +1 more source