Results 71 to 80 of about 91,797 (279)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Translating Plain Language An inquiry into the nature and strategies for successful plain language translation [PDF]

open access: yes, 2012
As plain language is increasing in popularity, the author looks at the intersection of plain language and translation in the context of transforming non-plain language text into plain language.
McCann, William
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Using Plain Language to Simplify Complex Legal Terms in the Banking Sector: The Case for African Languages in the South African Banks

open access: yesInternational Journal of Applied Research in Business and Management
Plain language refers to the use of understandable language in consumer documents. This is done to prevent practices wherein vulnerable consumers enter into agreements with banks while they do not fully understand the content and consequences of the ...
Menzi Zamokwakhe Thango
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Exposing Errors and Removing Errors: Pushing the Boundaries in Legal English

open access: yesAltre Modernità, 2017
As is well known, the language of the law tends to be relatively conservative in its style when compared with most other varieties of language. However, in recent decades we have witnessed a minor revolution in the way legal English has developed ...
Christopher Williams
doaj   +1 more source

Considering plain language: Issues and initiatives

open access: yes, 2010
Purpose: The purpose of this paper is to review the literature on plain language in Australia, the UK and the USA since the movement began to accelerate in the early 1960s; to review the progress of plain-language initiatives in those countries in the ...
Petelin, Roslyn
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Adaptation of Informed Consent for Anaesthesia to Plain Language Standard

open access: yes, 2022
Introduction.The paper describes the process of editing and validating documents on the basis of which a patient gives their informed consent for anaesthesia before surgery.
Tymiński, Radosław; The Law Firm Radosław Tymiński, Warsaw, Poland   +2 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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