Results 81 to 90 of about 3,310,049 (341)

Plain Language in Law in Hungary [PDF]

Acta Universitatis Sapientiae, Philologica, 2019
Abstract Plain language movement has a long history and has achieved significant changes in the USA and in many European countries. However, the situation is not as good as that in Hungary, especially in the field of law. As a researcher in two empirical “law and language” projects in Hungary since 2000, the author presents her ...
openaire   +3 more sources

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Improving readability of informed consents for research at an academic medical institution

Journal of Clinical and Translational Science, 2017
IntroductionThe final rule for the protection of human subjects requires that informed consent be “in language understandable to the subject” and mandates that “the informed consent must be organized in such a way that facilitates comprehension.” This ...
Kristie B. Hadden, Latrina Y. Prince, Tina D. Moore, Laura P. James, Jennifer R. Holland, Christopher R. Trudeau   +5 more
doaj   +1 more source

Optimizing Readability and Format of Plain Language Summaries for Medical Research Articles: Cross-sectional Survey Study

Journal of Medical Internet Research, 2020
Background Plain language summaries (PLSs) are intended to provide readers with a clear, nontechnical, and easily understandable overview of medical and scientific literature; however, audience preferences for specific PLS formats have yet to be fully ...
Leia Martínez Silvagnoli, Caroline Shepherd, J. Pritchett, J. Gardner   +3 more
semanticscholar   +1 more source

Imperial strategy of cancer cells through mitochondrial transfer

Molecular Oncology, EarlyView.
Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley   +1 more source

Returning aggregate results of clinical trials: Empirical data of patient preferences

Journal of Clinical and Translational Science, 2018
Introduction:The purpose of this research was to understand the preferences of patients receiving integrative medicine services for return of aggregate study results.Methods:A brief online survey (survey 1) was sent to 341 cancer patients receiving ...
Carmen E. Aldinger, Jennifer Ligibel, Im Hee Shin, John W. Denninger, Barbara E. Bierer   +4 more
doaj   +1 more source

Where are biomedical research plain‐language summaries?

Health Science Reports, 2020
Plain‐language summaries (PLS) are being heralded as a tool to improve communication of scientific research to lay audiences and time‐poor or nonspecialist healthcare professionals.
H. FitzGibbon, K. King, C. Piano, Carolyn Wilk, Mary Gaskarth   +4 more
semanticscholar   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Scientific abstracts and plain language summaries in psychology: A comparison based on readability indices

PLoS ONE, 2020
Findings from psychological research are usually difficult to interpret for non-experts. Yet, non-experts resort to psychological findings to inform their decisions (e.g., whether to seek a psychotherapeutic treatment or not).
Johannes Stricker, Anita Chasiotis, Martin Kerwer, Armin Günther   +3 more
semanticscholar   +1 more source