Results 101 to 110 of about 57,146 (267)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Final year high school examination texts of South African home and first additional language subjects

open access: yes, 2022
This data collection consists of reading comprehension and summary writing texts. The texts comprise of the final year high school exam texts for Home Language (HL) and First Additional Language (FAL) subjects written in South Africa between 2008 and
van Zaanen, Menno, Sibeko, Johannes
core  

Snapshots - a lay language summary of employment for military veterans [PDF]

open access: yes, 2018
A plain language summary of research and evidence relating to the UK Armed Forces and veteran ...
Cooper, Linda
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Plain language summary regarding the use of electronic cigarettes and smoking cessation

open access: yes, 2019
McGrory, John W. (2019). Plain language summary regarding the use of electronic cigarettes and smoking cessation.
McGrory, John W
core  

Plain language summary for publication: Neurexan's calming effect correlates to individual trait anxiety levels

open access: yes
This is a plain language summary of a published peer-reviewed article English, German, Spanish and Russian. It refers to a clinical trial demonstrating calming effects of Neurexan in the subgroup of study participants with increased anxiety level.
Johan van der Meer (11765180)   +10 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Plain language summary for publication: Vertigoheel improves different types of memory

open access: yes
This is a plain language summary of a published peer-reviewed article in English, German, Spanish and Russian. It refers to a preclinical study investigating Vertigoheel’s effect on cognitive performance in rodents. This summary was not peer-reviewed but
Kathrin Weyer (4063507)   +2 more
core   +1 more source

Advances in the management of allergic rhinitis: clinical relevance of the mometasone furoate–olopatadine association and the challenge of patient self-diagnosis and self-treatment

open access: yesDrugs in Context
Allergic rhinitis is a highly prevalent inflammatory disease that significantly impairs sleep, daily functioning and quality of life, with symptoms increasingly amplified by environmental changes such as prolonged pollen seasons and urban pollution ...
Maria D’Amato, Gennaro D’Amato
doaj   +1 more source

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